Blooms Syndrome Protein Blm Antibody Summary
| Immunogen |
The immunogen recognized by this antibody maps to a region between residues 1 and 50 of mouse Bloom Syndrome Homolog using the numbering given in entry NP_031576.2 (GeneID 12144). |
| Isotype |
IgG |
| Clonality |
Polyclonal |
| Host |
Rabbit |
| Gene |
BLM |
| Purity |
Immunogen affinity purified |
| Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
| Dilutions |
- Immunoprecipitation 1-4 ug/mg of lysate
|
| Application Notes |
This antibody is useful for Immunoprecipitation. For WB use rabbit anti-BLM antibody NB 100-1590 for WB of mouse BLM. |
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze. |
| Buffer |
Tris-Citrate/Phosphate (pH 7.0 - 8.0) |
| Preservative |
0.09% Sodium Azide |
| Concentration |
1.0 mg/ml |
| Purity |
Immunogen affinity purified |
Alternate Names for Blooms Syndrome Protein Blm Antibody
Background
Bloom syndrome protein (BLM) is a RecQ DNA-helicase that plays a role in DNA replication and repair. Mutations and inactivation of BLM result in human syndromes characterized by dwarfism, infertility, erythema, learning disabilities, immune deficiency and predisposition to cancer. BLM has been shown to associate with the BRCA1-associated genome surveillance complex (BASC) which contains BRCA1, MSH2, MSH6, MLH1, ATM, PMS2 and the RAD50-MRE11-NBS1 protein complex. BLM is also known as RecQ protein-like 3, DNA helicase, RecQ-like type 2, RECQ2, RECQL2, RECQL3, BS, MGC126616, MGC131618, and MGC131620.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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FAQs for Blooms Syndrome Protein Blm Antibody (NB100-1588) (0)
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