Bcl-10 Antibody (4F8)

Name: Bcl-10 Antibody (4F8)
Brand: Novus Biologicals
SKU: NB100-2180
Price: 299 USD
Availability: Discontinued

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Catalog Number

NB100-2180
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Bcl-10 Antibody (4F8) Summary

Immunogen	Purified recombinant fragment of human Bcl10 expressed in E. coli.
Specificity	BCL-10 (4F8E8H8)
Isotype	IgG1
Clonality	Monoclonal
Host	Mouse
Gene	BCL10
Purity	Protein A or G purified
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Applications/Dilutions

Dilutions	ELISA 1:10000 Flow Cytometry 1:200 - 1:400 Immunocytochemistry/ Immunofluorescence 1:200 - 1:1000 Immunohistochemistry 1:10 - 1:500 Immunohistochemistry-Paraffin 1:200 - 1:1000 Western Blot 1:500 - 1:2000
Application Notes	IHC(P): Dilution 1: 100- 1: 500 IHC(F): Dilution 1: 200- 1: 1000 Western blot: Dilution 1: 2000- 1: 5000 ELISA: Propose dilution 1: 10000. Determining optimal working dilutions by titration test.
Theoretical MW	26 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer	PBS
Preservative	0.03% Sodium Azide
Concentration	1 mg/ml
Purity	Protein A or G purified

Alternate Names for Bcl-10 Antibody (4F8)

B-cell CLL/lymphoma 10CIPERCLAPB-cell lymphoma/leukemia 10
Bcl10
Bcl-10
CARD-containing apoptotic signaling protein
CARD-containing molecule enhancing NF-kappa-B
CARD-containing proapoptotic protein
CARD-like apoptotic protein
CARMEN
caspase-recruiting domain-containing protein
cCARMEN
c-E10
c-E10bcl-10
CED-3/ICH-1 prodomain homologous E10-like regulator
Cellular homolog of vCARMEN
cellular-E10
CIPER
CLAP
hCLAP
Mammalian CARD-containing adapter molecule E10
mE10
mE10CARD containing molecule enhancing NF-kB

Background

Bcl-10 is a 31kDa protein containing a caspase recruitment domain (CARD). It plays an important role in apoptosis and activating NF-kappaB. The research suggested that it interacted with other CARD domain containing proteins including CARD9, 10, 11 and 14, which were thought to function as upstream regulators in NF-kappaB signaling. Bcl-10 is found to form a complex with MALT1 which encoded by another gene known to be translocated in MALT lymphoma. MALT1 and Bcl-10 are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bcl-10 Antibody
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NB100-2180

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Applications: WB, ELISA, Flow, ICC/IF, IHC

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Bioinformatics

Gene Symbol	BCL10
Entrez	8915(Human)

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Antibodies Secondary Antibodies Isotype Controls Proteins and Peptides ELISA Kits Sample Size New Products	About Us Careers Novus Guarantee Contact Us Our Team	Technical Support FAQs Protocols

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Bcl-10 Antibody (4F8)

Species Glossary

Images

Product Details

Order Details

Bcl-10 Antibody (4F8) Summary

Applications/Dilutions

Reactivity Notes

Packaging, Storage & Formulations

Alternate Names for Bcl-10 Antibody (4F8)

Background

Limitations

Customers Who Viewed This Item Also Viewed...

Publications for Bcl-10 Antibody (NB100-2180) (0)

Reviews for Bcl-10 Antibody (NB100-2180) (0)

Product General Protocols

Video Protocols

FAQs for Bcl-10 Antibody (NB100-2180) (0)

Secondary Antibodies

Isotype Controls

Additional Bcl-10 Products

Research Areas for Bcl-10 Antibody (NB100-2180)

Blogs on Bcl-10

Contact Information

Product PDFs

Calculators

Review this Product

Bioinformatics