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alpha-2A Adrenergic R/ADRA2A Antibody

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Order Details


    • Catalog Number
      NBP1-19562
    • Availability
      Product Discontinued

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alpha-2A Adrenergic R/ADRA2A Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 331-380 of Human AR-alpha2A.
Clonality
Polyclonal
Host
Rabbit
Gene
ADRA2A
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:50-1:200
  • Immunohistochemistry 1:50-1:200
  • Immunohistochemistry-Paraffin 1:50-1:200
  • Western Blot 1:500-1:1000
Theoretical MW
48 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for alpha-2A Adrenergic R/ADRA2A Antibody

  • a-2A AdrenergicR
  • ADRA2
  • ADRA2A
  • ADRA2Ralpha-2-adrenergic receptor, platelet type
  • ADRARZNF32
  • adrenergic, alpha-2A-, receptor
  • Alpha-2 adrenergic receptor subtype C10
  • alpha-2A Adrenergic R
  • alpha-2A adrenergic receptor
  • alpha2A AdrenergicR
  • Alpha-2A adrenoceptor
  • Alpha-2A adrenoreceptor
  • alpha-2AAR subtype C10
  • ALPHA2AAR
  • Alpha-2AAR
  • ZNF32

Background

This study investigates the involvement of alpha2-adrenergic receptors (AR) in mouse brain induced by a low dose of methamphetamine (METH, 2 mg/kg). Immunohistochemical studies show that alpha2A-AR increased in the dentate gyrus area of the hippocampus 24 h after five repeated administrations of METH. The hippocampal alpha2A-AR proteins rose 3.2-fold when compared to the saline-administered mice. The other adrenergic receptor, alpha1D-AR, were not changed by the treatment. Moreover, alphao-subunits of GTP-binding proteins (Galphao), one of the downstream molecules of alpha2A-AR, was also increased by the treatment. These suggest that the repeated administration of low-doses of METH causes quantitative changes of the signaling of alpha2A-AR in the mouse hippocampus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for alpha-2A Adrenergic R/ADRA2A Antibody (NBP1-19562) (0)

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for alpha-2A Adrenergic R/ADRA2A Antibody (NBP1-19562). (Showing 1 - 2 of 2 FAQ).

  1. Can you please specify whether blocking peptides are available for the following antibodies? NBP1-19562 and NBP1-67832
    • Unfortunately we do not have any blocking peptides available for these antibodies at this time. If we had them available they would be under the same catalog number with a PEP at the end of it.
  2. Do you have any reference regarding the use of the antibodies NBP1-19562 and NBP1-67832 on rat brain?
    • At this time we do not have any product specific references available, but will guarantee the use in rat as it is indicated on the datasheet. If the protein is expressed in the customer's rat samples then they can receive a full refund or replacement should it not work as specified.

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Bioinformatics

Gene Symbol ADRA2A
Entrez
Uniprot