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ABCG2 Antibody (NB120-3379)

ABCG2 Antibody (BXP-34)

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ABCG2 Antibody (BXP-34) Summary:
Species:Hu
Applications:ICC, IHC-Fr
Clonality:Monoclonal
Gene:ABCG2
Purity:Tissue culture supernatant
Host:Mouse
Specificity:This does not cross react with the human MDR 1, MRP 1, MRP 2,or MRP 5 gene products.
Publications:Antibody has at least 4 Background References.
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
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ABCG2 Antibody (BXP-34) Details:
Clone:BXP-34
Isotype:IgG
Immunogen:BCRP over-expressing cell line MCF 7 MR.
Marker:Hematopoietic Stem Cell Marker
Epitope:Internal epitope.
Species Reactivity:

Cross-reacts with Human.Not yet tested in other species.

Applications:
Uses:This antibody does not work in Western blot. Optimal dilutions / concentrations should be determined by the end user.
Dilutions:Immunocytochemistry, Immunohistochemistry-Frozen,
Unit Size:0.1 ml
Concentration:This product is unpurified. Concentration is not relevant.
Positive Controls:1 Positive Controls
Packaging:
Storage:Store at 4 °C. Do not freeze.
Buffer:PBS
Preservative:0.1% Sodium Azide
Limitations:This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Gene Symbol: ABCG2
Entrez9429 (Human)
 
Background:

Breast Cancer Resistance Protein (BCRP) is a 70 kDa ATP-Binding Cassette membrane transport protein involved in multidrug resistance. BCRP may be over-expressed in cancer cell lines selected with doxorubicin / verapamil, topotecan or mitoxantrone.

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Publications (4)

ABCG2 Antibody (BXP-34) Background References:

  1. Doyle LA, et al. A Multidrug resistance transporter from human MCF-7 breast cancer cells Proc Natl Acad Sci USA 95:15665-15670, 1998.
  2. Scheffer GL. Breast Cancer Resistance Protein is localized at the plasma membrane in mitoxantrone topotecan resistant cell lines. Cancer Res 60:2589-93, 2001.

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