NOD2 Products | Novus Biologicals

NOD2 Products

NOD2 Primary Antibodies

20 NOD2 Antibodies including 13 polyclonal and 7 monoclonal antibodies. (view)

NOD2 Antibody Packs

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NOD2 Lysates

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NOD2 Peptides and Proteins

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NOD2 (nucleotide-binding oligomerization domain containing 2) is a member of the apoptosis regulating protein family that includes caspase recruitment-domains, as well as Apaf-1 and NOD1. It contains two N-terminal CARDs, a nucleotide binding domain (NBD), and multiple C-terminal leucine-rich repeats (LRRs). NOD2 is expressed in monocytes (whereas NOD1 is expressed in multiple tissues). NOD2 plays a role in regulating NF-kappaB. It also acts as an intracellular receptor for bacterial lipopolysaccharides and contributes to inflammatory bowel disease (IBD) and Crohn's disease.

Gene ID: 64127

(see alternate names)

BLAU , CARD15caspase recruitment domain protein 15 , caspase recruitment domain family, member 15 , Caspase recruitment domain-containing protein 15 s, CDACUG , CLR16.3 , IBD1NLR family, CARD domain containing 2 , Inflammatory bowel disease protein 1 , NLRC2 , NOD-like receptor C2 , nucleotide-binding oligomerization domain 2 , nucleotide-binding oligomerization domain containi, nucleotide-binding oligomerization domain, leucine, nucleotide-binding oligomerization domain-containi, PSORAS1NOD2B