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WT1 Antibody

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Product Details

Summary
Product Discontinued
View other related WT1 Primary Antibodies

Order Details


    • Catalog Number
      NB120-15250
    • Availability
      Product Discontinued

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WT1 Antibody Summary

Immunogen
Synthetic peptide (Human) (C terminal).
Localization
Cytoplasmic and Nuclear
Specificity
Wilms Tumor
Clonality
Polyclonal
Host
Rabbit
Gene
WT1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin Neat
Application Notes
IHC-P: Use neat for 10 min at RT. Boil tissue sections in 10mM Citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user.

Reactivity Notes

Cross-reacts with Human, Mouse and Rat.Not yet tested in other species.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
10mM PBS (pH 7.4) and BSA
Preservative
Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for WT1 Antibody

  • AWT1
  • GUD
  • NPHS4GUD
  • WAGR
  • Wilms tumor 1
  • Wilms tumor protein
  • WIT-2
  • WT1
  • WT33

Background

WT1 encodes multiple isoforms of a zinc finger transcription factor essential for correct mammalian urogenital development. Different WT1 isoforms are thought to regulate transcription and participate in mRNA processing, functions reflected by a complex sub-nuclear distribution. In humans, the preservation of the correct isoform ratio and their localization has been reported to be vital, and its disruption to result in disease. This gene has been reported as a useful marker for several types of illnesses. Mutations in this gene lead to the development of Wilm's Tumor, a sporadic and familial childhood kidney tumor.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NB120-15250
WT1 Antibody
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Bioinformatics

Gene Symbol WT1
Entrez