Thyroglobulin Antibody (NB500-571)

Thyroglobulin Antibody (2H11)

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Thyroglobulin Antibody (2H11) Summary:
Species:Hu
Applications:IHC-P
Clonality:Monoclonal
Gene:TG
Purity:Protein A purified
Host:Mouse
Specificity:NB500-571 recognises antigen thyroglobulin (TG).
Publications:Antibody has at least 3 Background References.
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
View Additional Thyroglobulin Products
Thyroglobulin Antibody (2H11) Details:
Clone:2H11
Isotype:IgG1
Immunogen:thyroid follicular cells (Human)
Species Reactivity:

Reacts with Human.

Applications:
Uses:Immunohistochemistry - Paraffin Recommend 1 hour at room temperature. Perform heat mediated antigen retrieval via the microwave method before commencing with IHC staining protocol, by using 0.01M citrate buffer, pH 6.
Dilutions:Immunohistochemistry-Paraffin 1:200
Unit Size:0.1 mg
Concentration:1.0 mg/ml
Packaging:
Storage:Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles.
Preservative:15mM Sodium Azide
Limitations:This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Gene Symbol: TG
Entrez7038 (Human)
 
Background:

Thyroglobulin is the glycoprotein precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is obtained from the thyroid gland and exhibits the general properties of the globulins. The human thyroglobulin (hTG) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti thyroglobulin autoantibodies were the first factor to be discovered. Anti hTG is found in all thyroid autoimmune diseases (Hashimoto's thyroiditis, Graves diseases), with the highest level observed in Hashimoto's thyroiditis. Anti hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients.

Jump to: Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies

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Thyroglobulin in Context


Novus Explorer for Thyroglobulin gene

Try our bioinformatic tool that shows the relationships between TG and other genes, diseases, pathways and post-translational modifications.