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Thrombospondin-1 Antibody (SPM321)

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Product Details

Summary
Product Discontinued
View other related Thrombospondin-1 Primary Antibodies

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    • Catalog Number
      NBP1-39864
    • Availability
      Product Discontinued

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Thrombospondin-1 Antibody (SPM321) Summary

Immunogen
Reduced and alkylated purified human TSP (fully denatured) from the supernatant of thrombin- activated platelets
Specificity
Reduced and alkylated purified human TSP (fully denatured) from the supernatant of thrombin- activated platelets
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
THBS1
Purity
Protein G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10-1:1000
  • Immunocytochemistry/ Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 5 ug/ml
  • Immunoprecipitation 2 ug/ml
  • Western Blot 1-2 ug/ml
Application Notes
This antibody is useful in Western Blot , Immunoprecipitation (2 ug/ml), Flow Cytometry, Immunofluorescence, Immunohistochemistry-Paraffin (5 ug/ml).

Reactivity Notes

Human. Predicted cross-reactivity based on sequence identity: Bovine, Mouse, Porcine, Rat

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4) and 0.2% BSA
Preservative
0.05% Sodium Azide
Concentration
0.2 mg/ml
Purity
Protein G purified

Alternate Names for Thrombospondin-1 Antibody (SPM321)

  • THBS
  • THBS1
  • THBS-1
  • thrombospondin 1
  • Thrombospondin1
  • Thrombospondin-1
  • thrombospondin-1p180
  • TSP-1
  • TSP1thrombospondin-1
  • TSPTSP-1

Background

The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Research Areas for Thrombospondin-1 Antibody (NBP1-39864)

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Blogs on Thrombospondin-1.

AHR - A transcription factor regulating immunity and tumorigenesis
The aryl hydrocarbon receptor (AHR) is a ligand activated transcription factor that controls the expression of a diverse set of genes. In the absence of ligand, AHR is retained in the cytoplasm. Upon ligand binding AHR translocates to the nucleus w...  Read full blog post.

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Bioinformatics

Gene Symbol THBS1
Entrez
Uniprot