TRADD Antibody (NBP1-67733) | Novus Biologicals

TRADD Antibody (NBP1-67733) (0.05 mg)

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	Catalog Number	NBP1-67733
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anti-tumor necrosis factor receptor-1-associated protein antibody, anti-tumor necrosis factor receptor type 1-associated DEATH domain protein antibody, anti-tumor necrosis factor receptor type 1 associated death domain protein antibody, anti-MGC11078 antibody, anti-TNFRSF1A-associated via death domainTNFR1-associated DEATH domain protein antibody

TRADD Antibody Summary:

Species:	Hu, Mu	Gene:	TRADD
Applications:	WB, ELISA, IHC	Purity:	Immunogen affinity purified
Clonality:	Polyclonal	Host:	Rabbit
Specificity:	TRADD Antibody detects endogenous levels of total TRADD protein.
Publications:

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RNAi
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TRADD Antibody Details:

Isotype:	IgG
Immunogen:	The antiserum was produced against synthesized peptide derived from human TRADD. The immunogen region is: C-terminal.

Species Reactivity:

Human,Mouse

Applications:

Uses:	This product is useful for Western Blot Immunohistochemistry ELISA.
Dilutions:	Western Blot, Immunohistochemistry 1:50-1:100, ELISA 1:5000
Unit Size:	0.05 mg (also available: 0.1 mg)
Concentration:	1 mg/ml

Packaging:

Storage:	Store at -20°C. Avoid freeze-thaw cycles.
Buffer:	phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, and 50% glycerol.
Preservative:	0.02% Sodium Azide
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.

Gene Symbol: TRADD

Uniprot:	Q15628 (Human)

Related Genes:

Background:

The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq]

Images (2)


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TRADD Antibody Images (2)

	Western Blot: TRADD Antibody [NBP1-67733] - Western blot analysis of extracts from COS7 cells, using TRADD Antibody. The lane on the right is treated with the synthesized peptide.

	Immunohistochemistry-Paraffin: TRADD Antibody [NBP1-67733] - Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using TRADD Antibody. The picture on the right is treated with the synthesized peptide.