PARP Antibody (NB100-77326)

PARP Antibody

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PARP Antibody Summary:
Species:Hu
Applications:IHC-P
Clonality:Polyclonal
Gene:PARP1
Purity:Immunogen affinity purified
Host:Rabbit
Specificity:PARP1
 
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
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PARP Antibody Details:
Isotype:IgG
Immunogen:The epitope recognized by this antibody maps to a region between residue 50 and 100 of human poly (ADP-ribose) polymerase family, member 1 using the numbering given in entry NP_001609.1 (GeneID 142).
Species Reactivity:

Human.

Applications:
Uses:This antibody is useful for immunohistochemistry on paraffin sections. Epitope exposure with citrate bufferexposure is recommended. Epitope exposure with citrate buffer will enhance staining. Likely to work with frozen sections. In some cases, the antibody may be diluted further than indicated.
Dilutions:Immunohistochemistry-Paraffin 1:100-1:500
Unit Size:0.1 ml
Concentration:Please see the vial label for concentration.
Packaging:
Storage:Store at 4 °C. Do not freeze.
Buffer:Tris-buffered Saline containing 0.1% BSA
Preservative:0.09% Sodium Azide
Limitations:This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Gene Symbol: PARP1
Entrez142 (Human)
Swiss ProtNP_001609.1 (Human)
 
Background:

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

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Working with PARP

PARP Antibody Images (2)
Immunohistochemistry: PARP1 Antibody [NB100-77326] - Detection of Human PARP1 by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody:Affinity purified rabbit anti-PARP1 (NB100-77326) used ata dilution of 1:250. Detection: DAB staining.Immunohistochemistry: PARP1 Antibody [NB100-77326] - Detection of Human PARP1 by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody:Affinity purified rabbit anti-PARP1 (NB100-77326) used ata dilution of 1:250. Detection: DAB staining.
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Jump to: Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies

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PARP in Context


Research Areas related to PARP (7):
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