NFkB p65 Antibody (NB100-97832)
NFkB p65 Antibody
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Distributor Data...
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anti-RELA antibody, anti-reticuloendotheliosis viral oncogene homolog A antibody, anti-p65. antibody, anti-nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 antibody, anti-NFKB3 antibody, anti-NF-kappaB3 antibody, |
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NFkB p65 Antibody Summary: | | Gene: | RELA |
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| Purity: | Immunogen affinity purified |
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| Host: | Rabbit |
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| | | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional NFkB p65 Products NFkB p65 Antibody Details: | Isotype: | IgG |
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| Immunogen: | The epitope recognized by this antibody maps to a region between residue 501 and 551 of human reticuloendotheliosis viral oncogene homolog A using the numbering given in entry NP_068810.2 (GeneID 5970). |
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| Uses: | This antibody is useful for western blot and immunoprecipitation. |
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| Dilutions: | Western Blot 1:2000-1:10000,
immunoprecipitation 2-5 mcg/mg lysate, |
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| Unit Size: | 0.1 ml |
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| Concentration: | 1.0 mg/ml |
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| Positive Controls: | 1 Positive Controls |
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Packaging: | Storage: | Store at 4 °C. Do not freeze. |
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| Buffer: | Tris-citrate/phosphate buffer, pH 7 to 8 |
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| Preservative: | 0.09% Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA, or RELB (MIM 604758) to form the NFKB complex. The p50 (NFKB1)/p65 (RELA) heterodimer is the most abundant form of NFKB. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008 or NFKBIB, MIM 604495), which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664, or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NFKB complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).[supplied by OMIM]
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Images (1) Reviews (0) Related Products (91) Exploring NFkB p65
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Working with NFkB p65
NFkB p65 Antibody Images (1) Western Blot and Immunoprecipitation: RelA Antibody [NB100-97832] - Detection of Human and Mouse RelA/p65 on HeLa whole cell lysate using NB100-97832. RelA/p65 was also immunoprecipitated by rabbit anti-RelA/p65 antibody NB100-97831. |
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Jump to: Positive Controls, Antibody Pairs, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsPositive ControlsAntibody Pairs (8)Lysates (1)Peptides and ProteinsPrimary Antibodies (40)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| NFkB p65 Antibody | NBP1-96139 | Hu, Mk, Mu | ICC, IF, IHC-P, WB | (3) | | | | | NFkB p65 Antibody | NBP1-96138 | Hu, Mk, Mu | ICC, IF, IHC-P | (2) | | | | | NFkB p65 Antibody (E379) | NB110-57267 | Hu, Mu | FACS, ICC, IHC-P, IP, WB | (3) | (1) | | | | NFkB p65 Antibody (27F9.G4) | NBP1-77815 | Hu | ELISA, IF, IHC-P, WB | (4) | | | | | NFkB p65 Antibody | NB100-2176 | Hu, Mu, Rt | IHC-P, IP, WB | (3) | (1) | | | | ... and 35 more. See All » |
RNAi (1)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Rabbit IgG Antibody [HRP] | NB730-H | Rb | ELISA, ICC, IHC-P, WB | | (5) | | | | Rabbit IgG Antibody [FITC] | NB730-F | Rb | ICC, IHC-P | | (1) | | | | Rabbit IgG Antibody [Biotin] | NB730-B | Rb | ELISA, ICC, IHC-P, WB | | | | | | Rabbit IgG, H/L Chains Antibody [DyLight 488] | NBP1-72944 | Rb | FLISA, IF, WB | (3) | | | | | Rabbit IgG Antibody [Alkaline Phosphatase] | NB730-AP | Rb | ELISA, ICC, IHC-P, WB | | (1) | | | | See All » |
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