CDK2 Antibody Summary
| Immunogen |
Synthetic peptide (Human) conjugated to KLH. |
| Localization |
Cytoplasmic and Nuclear |
| Specificity |
No reaction was observed against other related cyclin dependent kinases. |
| Clonality |
Polyclonal |
| Host |
Rabbit |
| Gene |
CDK2 |
| Purity |
Unpurified |
| Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
| Dilutions |
- ELISA 1:1000 - 1:5000
- Immunohistochemistry 1:200 - 1:1000
- Immunoprecipitation 1:100
- Western Blot 1:200 - 1:1000
|
| Application Notes |
Anti-cdk2 antbody is suitable for immunohistochemistry, western blotting and other antibody based assays. Multiple isoforms as well as phosphorylated forms of cdk-2 may be detected by this antibody. use paraffin embedded tissues for immunohistochemistry. |
Reactivity Notes
Cross-reacts with Human and Rat. Not yet tested in other species.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Buffer |
None |
| Preservative |
0.01% Sodium Azide |
| Purity |
Unpurified |
Alternate Names for CDK2 Antibody
Background
The protein encoded by the Cdk2 gene is a member of the Ser/Thr protein kinase family. This protein kinase is highlysimilar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of thecyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycleG1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex includingcyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its proteinphosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have beenreported. (provided by RefSeq)
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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