BDNF Antibody (H00000627-B01P)

BDNF Antibody

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BDNF Antibody Summary:
Species:Hu
Applications:ELISA, WB
Clonality:Polyclonal
Gene:BDNF
Purity:Whole antisera
Host:Mouse
Specificity:BDNF
 
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
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BDNF Antibody Details:
Immunogen:BDNF (AAH29795, 1 a.a. ~ 248 a.a) full-length human protein.
Epitope:MTILFLTMVISYFGCMKAAPMKEANIRGQG GLAYPGVRTHGTLESVNGPKAGSRGLTSLA DTFEHMIEELLDEDQKVRPNEENNKDADLY TSRVMLSSQVPLEPPLLFLLEEYKNYLDAA NMSMRVRRHSDPARRGELSVCDSISEWVTA ADKKTAVDMSGGTVTVLEKVPVSKGQLKQY FYKTKCNPMGYAKEGCRGIDKRHWNSQCRT TQSYVRALTMDSKKRIGWRFIRIDTSCVCT LTIKRGR*
Species Reactivity:

Human. Other species not tested.

Applications:
Uses:Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.
Dilutions:ELISA, Western Blot 1:500
Unit Size:0.05 mg
Concentration:This product is unpurified. Concentration is not relevant.
Positive Controls:1 Positive Controls
Notes:
This product is produced by and distributed for Abnova, a company based in Taiwan.
Packaging:
Storage:Aliquot and store at -20 °C or -80 °C. Avoid freeze-thaw cycles.
Buffer:This is unpurified antiserum so it is not possible to supply the specific antibody concentration.
Preservative:No Preservative
Limitations:This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Gene Symbol: BDNF
Entrez627 (Human)
OMIM113505, 164230,
Swiss ProtAAH29795 (Human)
 
Background:

BDNF belongs to the neurotrophin family and promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. It is a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. The alterations in BDNF expression induced by various kinds of brain insult including stress, ischemia, seizure activity and hypoglycaemia, may contribute to some pathologies such as depression, epilepsy, Alzheimer's, and Parkinson's disease. Subunit: Monomers and homodimers. Binds to NTRK2/TRKB. Subcellular Location: Secreted protein. Post translation modification: Converted into mature BDNF by plasmin (PLG). Similarity: Belongs to the NGF-beta family.

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Working with BDNF

BDNF Antibody Images (2)
Western Blot: BDNF Antibody [H00000627-B01P] - Western Blot analysis of BDNF expression in transfected 293T cell line (H00000627-T01) by BDNF MaxPab polyclonal antibody. Lane 1: BDNF transfected lysate(27.28 KDa). Lane 2: Non-transfected lysate.Western Blot: BDNF Antibody [H00000627-B01P] - BDNF MaxPab polyclonal antibody. Western Blot analysis of BDNF expression in NIH/3T3.
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Jump to: Positive Controls, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies

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Positive Controls
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Peptides and Proteins
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RNAi (6)
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Secondary Antibodies
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BDNF in Context


Research Areas related to BDNF (3):
Novus Explorer for BDNF gene

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