ATF4 Antibody (NB100-81801)

ATF4 Antibody

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ATF4 Antibody Summary:
Species:Hu
Applications:IHC
Clonality:Polyclonal
Gene:ATF4
Purity:Immunogen affinity purified
Host:Rabbit
Specificity:ATF4 (specific to a.a. 245) detects endogenous levels of total ATF4 protein.
Publications:Antibody has at least 1 Background Reference.
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
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ATF4 Antibody Details:
Isotype:IgG
Immunogen:The antiserum was produced against synthesized non-phosphopeptide derived from human ATF4 around the phosphorylation site of serine 245 (N-R-SP-L-P)..
Species Reactivity:

Human

Applications:
Uses:Immunohistochemistry
Dilutions:immunohistochemistry 1:50-1:100
Unit Size:0.1 mg
Concentration:1.0 mg/ml
Positive Controls:1 Positive Controls
Packaging:
Storage:Aliquot and store at -20 °C or -80 °C. Avoid freeze-thaw cycles.
Buffer:phosphate buffered saline (without Mg2+and Ca2+), pH 7.4, 150mM NaCl, and 50% glycerol.
Preservative:0.02% Sodium Azide
Limitations:This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Gene Symbol: ATF4
Entrez468 (Human)
Swiss ProtP18848 (Human)
 
Background:

ATF4 is a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain (referenced from Entrez gene).

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Working with ATF4

ATF4 Antibody Images (1)
Immunohistochemistry: ATF4 Antibody [NB100-81801] - Immunohistochemical analysis of human paraffin-embedded human breast carcinoma tissue using ATF4 (Ab-245) antibody.
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Publications (1)

ATF4 Antibody Background References:

  1. Yang X, et al. (2004). Cell.117(3): 387-398.

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Jump to: Positive Controls, Antibody Pairs, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies

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ATF4 in Context


Novus Explorer for ATF4 gene

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