ZAK Products | Novus Biologicals

ZAK Products

ZAK Primary Antibodies

13 ZAK Antibodies including 4 polyclonal and 9 monoclonal antibodies. (view)

ZAK Lysates

3 ZAK Lysates. (view)

ZAK Peptides and Proteins

2 ZAK Proteins. (view)

ZAK RNAi

2 ZAK RNAi. (view)

ZAK is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]

Gene ID: 51776

(see alternate names)

AZK , EC 2.7.11 , EC 2.7.11.25 , HCCS-4 , Human cervical cancer suppressor gene 4 protein sl, Leucine zipper- and sterile alpha motif-containing, mitogen-activated protein kinase kinase kinase MLT, mixed lineage kinase 7 , mixed lineage kinase with a leucine zipper and a s, mixed lineage kinase-related kinase MRK-beta , Mixed lineage kinase-related kinase , MLK-like mitogen-activated protein triple kinase s, MLK-related kinase , MLK7 , mlklak , MLT , MLTK , MRKcervical cancer suppressor gene 4 protein , pk , protein kinase , sterile alpha motif and leucine zipper containing , Sterile alpha motif- and leucine zipper-containing