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RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutiveand enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required foraccurate 3'-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participatesin the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T cell activation; anevent reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3'-splice site

Gene ID: 199746
FLJ35525 , MGC33901 , splicing factor U2AF 26 kDa subunit , U2 auxiliary factor 26 , U2 small nuclear RNA auxiliary factor 1-like 3 sli, U2 small nuclear RNA auxiliary factor 1-like 4 sli, U2 small nuclear RNA auxiliary factor 1-like prote, U2 small nuclear RNA auxiliary factor 1-like prote, U2(RNU2) small nuclear RNA auxiliary factor 1-like, U2(RNU2) small nuclear RNA auxiliary factor 1-like, U2AF1-like protein 3 , U2AF1-RS3 , U2AF1L3 , U2AF1L3V1 , U2AF1RS3 , U2af26