KOR Products

Description

Opioid is the term used to designate a group of compounds that are opium-like in their properties. These drugs have effects on perception of pain, consciousness, motor control, mood, and autonomic function, and can induce physical dependence. Pharmacological studies suggested that there are at least 3 major classes of opioid receptors, designated delta, kappa, and mu. They differ in their affinity for various opioid ligands and in their cellular distribution. Studies of the receptors in the mouse and rat show that they are structurally related and are members of the family of 7 transmembrane-spanning G protein-coupled receptors. The kappa opiod receptor inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. It is the receptor for beta-endorphin.

Bioinformatics

Entrez	4986 Human 18387 Mouse 29335 Rat
Uniprot	P41145
Product By Gene ID	4986
Alternate Names	kappa opioid receptor kappa-type opioid receptor KOR K-OR-1 KOR-1 Opiate receptor, kappa-1 opioid receptor, kappa 1 OPRK OPRK1 Oprk2 R21

Research Areas for KOR

Find related products by research area and learn more about each of the different research areas below.

GPCR
Signal Transduction