Novus Biologicals

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles.

Members of the 14-3-3 family of proteins are highly conserved proteins, localized in neurons, and are axonally transported to the nerve terminals. They are also present, at lower levels, in various other eukaryotic tissues. 14-3-3 proteins appear to play important roles in a variety of signal transduction pathways, including those involved in cell cycle regulation and cell survival. Because 14-3-3 proteins bind to specific phosphoserine-containing sequences they are likely to have an important role in signaling pathways mediated by serine/threonine protein kinases. Evidence indicates 14-3-3 is required for Raf 1 kinase activity and phosphorylation amoung many other functions.

Made to Sheep 14-3-3

Sheep. Not yet tested in other species.

This antibody is useful for Immunohistochemistry-Paraffin, immunoprecipitation, Western Blot

0.1 ml of Serum liquid

Sodium Azide