ACOX2 Antibody
Goat Polyclonal anti-ACOX2
Price: $295.00
  • Catalog Number: NB100-57853
  • Unit Size: 0.1 mg
Product Images
Western Blot: ACOX2 Antibody [NB100-57853] - NB100-57853 (0.5µg/ml) staining of Human Liver lysate (35µg protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence. 
Gene ID 8309 Reference Sequence NP_003491.1 
Species Summary Hu(+) Application Summary ELISA, WB 
Purity Immunogen affinity purified Host Goat 
Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Background

The product of this gene belongs to the acyl-CoA oxidases family. It encodes the branched-chain acyl-CoA oxidase which is involved in the degradation of long branched fatty acids and bile acid intermediates in peroxisomes. Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates, and may lead to Zellweger syndrome, severe mental retardation and death in children.
Isotype

IgG
Immunogen

Synthetic peptide, C-QWAQKSPTNTQENP, representing the internal region (near the C Terminus) of the human sequence according to NP_003491.1
Epitope

QWAQKSPTNTQENP
Species Reactivity

Reacts with Human.
Uses

Peptide ELISA and Western Blot In WB approx 75kDa band observed in Human Liver lysates (calculated MW of 76.8kDa according to NP_003491.1). An additional band of 37kDa was consistently observed, however this band was not blocked by the immunizing peptide and it is therefore a non-specific signal.

Dilutions

ELISA 1:4000, Western Blot 0.5-1.5ug/ml
Concentration

0.5 mg/ml
Positive Controls:

* Human Liver Protein NB820-59232
Packaging

0.1 mg Immunogen affinity purified Goat antisera.
Buffer

Tris-saline [ pH7.3] with 0.5% BSA
Preservative

0.02% sodium azide
Alternate Names

anti-ACOX2 antibody, anti-acyl-Coenzyme A oxidase 2, branched chain antibody, anti-BCOX antibody, anti-BRCACOX antibody, anti-BRCOX antibody, anti-THCCox antibody, anti-Peroxisomal branched chain acyl-CoA oxidase antibody, anti-THCA-CoA oxidase antibody, anti-Trihydroxycoprostanoyl-CoA oxidase antibody
Gene Symbol

ACOX2
 
 
 

Baumgart E, Vanhooren JC, Fransen M, Marynen P, Puype M, Vandekerckhove J, Leunissen JA, Fahimi HD, Mannaerts GP, van Veldhoven PP. Molecular characterization of the human peroxisomal branched-chain acyl-CoA oxidase: cDNA cloning, chromosomal assignment, tissue distribution, and evidence for the absence of the protein in Zellweger syndrome.Proc Natl Acad Sci U S A. 1996 Nov 26;93(24):13748-53. PMID: 8943006