ACSL5 Antibody
Goat Polyclonal anti-ACSL5
Price: $295.00
  • Catalog Number: NB100-2918
  • Unit Size: 0.1 mg
Product Images
NB 100-2918 (1?g/ml) staining of Human Spleen lysate (35?g protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 
Gene ID 51703 Reference Sequence NP_057318.2; NP_976313.1; NP_976314.1 
Species Summary Hu(+) Application Summary ELISA, WB 
Purity Immunogen affinity purified Host Goat 
Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Background

The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene.
Research Areas

Cancer,    

Immunogen

C-RTQIDSLYEHIQDC TerminusNP_057318.2; NP_976313.1; NP_976314.1
Species Reactivity

Reacts with Human.

Uses

Peptide ELISA: antibody detection limit dilution 1:16,000. Western Blot: Approx 75kDa band observed in Human Spleen lysates (calculated MW of 76.0kDa according to NP_976313.1and NP_976314.1). Recommended concentration: 1-3
Dilutions

ELISA , Western Blot

Positive Controls

Human Spleen lysate
Concentration

0.5 mg/ml
Positive Controls:

* Antigen standard for ACSL5 (NM_203379) (transient overexpression lysate)
Packaging

0.1 mg Immunogen affinity purified Goat antisera.
Buffer

Tris-saline containing 0.02% Na azide [pH7.3] with 0.5% BSA
Preservative

0.02% Sodium Azide
Alternate Names

anti-ACSL5 antibody, anti-acyl-CoA synthetase long-chain family member 5 antibody, anti-HGNC:16526 antibody, anti-ACS2 antibody, anti-ACS5 antibody, anti-FACL5 antibody, anti-fatty-acid-Coenzyme A ligase antibody, anti-long-chain 5 antibody, anti-long-chain acyl-CoA synthetase 5 antibody, anti-long-chain fatty ac antibody
Notes

This antibody is expected to recognise isoform a (NP_057318.2) and isoform b (NP_976313.1 and NP_976314.1).
Gene Symbol

ACSL5
 
 
 

Obermuller N, Keith M, Kopitz J, Autschbach F, Schirmacher P, Gassler N. Coeliac disease is associated with impaired expression of acyl-CoA-synthetase 5.Int J Colorectal Dis. 2005 Apr 5; [Epub ahead of print] PMID: 15809837