ACRV1 Antibody
Mouse Polyclonal anti-ACRV1 - acrosomal vesicle protein 1, MaxPab Antibody
Price: $295.00
  • Catalog Number: H00000056-B01
  • Unit Size: 0.05 ml
Product Images
Western Blot analysis of ACRV1 expression in transfected 293T cell line by ACRV1 MaxPab polyclonal antibody (B01).<br><br>Lane 1: ACRV1 transfected lysate(29.26 KDa).<br>Lane 2: Non-transfected lysate.<br> 
Gene ID 56 Reference Sequence  
Species Summary Hu(+) Application Summary ELISA, WB 
Purity  Host Mouse 
Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Background

This gene encodes a testis-specific, differentiation antigen, acrosomal vesicle protein 1, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. This gene consists of 4 exons and its alternative splicing generates multiple distinct transcripts, which encode protein isoforms ranging from 81 to 265 amino acids. The longest transcript is the most abundant, comprising 53-72% of the total acrosomal vesicle protein 1 messages; the second largest transcript comprises 15-32%; the third and the fourth largest transcripts account for 3.4-8.3% and 8.7-12.5%, respectively; and the remaining transcripts combined account for < 1% of the total acrosomal vesicle protein 1 message. It is suggested that phenomena of cryptic splicing and exon skipping occur within this gene. The acrosomal vesicle protein 1 may be involved in sperm-zona binding or penetration, and it is a potential contraceptive vaccine immunogen for humans.
Immunogen

ACRV1 (AAH14588, 1 a.a. ~ 266 a.a) full-length human protein.
Epitope

MNRFLLLMSLYLLGPARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPISSTSTGTILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCPSMNLFSHGTRMQIIC
Species Reactivity

Human. Other species not tested.
Uses

Antibody Reactive Against transfected protein with on ELISA and Western Blot. Untransfected protein used as a negative control.
Dilutions

Western Blot 1:500 ELISA
Positive Controls

H00000056-T01
Positive Controls:

* ACRV1 293T Cell Transient Overexpression Lysate (denatured)
Packaging

0.05 ml of mouse antisera with 50% glycerol.
Buffer

This antibody is in antisera and the concentration is unavailable.
Preservative

No Preservative
Alternate Names

anti-D11S4365 antibody, anti-SPACA2 antibody
Notes

This antibody is supplied by Abnova. The immunizing protein may also available for this product. Unit cost for the protein is $ 250 (2 ug), $ 305 (10 ug), and $ 445 (25 ug). MaxPab is a registered trademark of Abnova.
Gene Symbol

ACRV1