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![Western Blot: APCDD1 Antibody - BSA Free [NB110-92756] - APCDD1 knockdown potently (C) inhibited cell proliferation. Error bars represent mean +/- SD of three replicates (*P < 0.05, **P < 0.01, ***P < 0.001). (E) A673 and SKNMC cells stably expressing shMEIS1 were transiently transfected with plasmid encoding APCDD1, and subjected to immunoblotting and MTT assays. Bars represent mean +/- SD of three replicates (**P < 0.01). Image collected and cropped by CiteAb from the following publication (//academic.oup.com/nar/article/47/3/1255/5212009) licensed under a CC-BY license.](http://images.novusbio.com/fullsize/APCDD1-Antibody---BSA-Free-Knockdown-Validated-NB110-92756-img0004.jpg "<b>Genetic Strategies Validation. </b>Western Blot: APCDD1 Antibody - BSA Free [NB110-92756] - APCDD1 knockdown potently (C) inhibited cell proliferation. Error bars represent mean +/- SD of three replicates (*P < 0.05, **P < 0.01, ***P < 0.001). (E) A673 and SKNMC cells stably expressing shMEIS1 were transiently transfected with plasmid encoding APCDD1, and subjected to immunoblotting and MTT assays. Bars represent mean +/- SD of three replicates (**P < 0.01). Image collected and cropped by CiteAb from the following publication (//academic.oup.com/nar/article/47/3/1255/5212009) licensed under a CC-BY license.")
![<b>Genetic Strategies Validation. </b>Western Blot: APCDD1 Antibody [NB110-92756] - Detection of APCDD1 in human heart lysate](http://images.novusbio.com/fullsize/APCDD1-Antibody-Western-Blot-NB110-92756-img0003.jpg)
![Western Blot: APCDD1 Antibody - BSA Free [NB110-92756] - APCDD1 is co-regulated by MEIS1 & EWS-FLI1 & mediates the oncogenic role of MEIS1. (A, B) Silencing of (A) MEIS1 or (B) EWS-FLI1 downregulated expression of both APCDD1 mRNA & protein. Error bars represent mean ± SD of three replicates (**P < 0.01, ***P < 0.001). (C, D) APCDD1 knockdown potently (C) inhibited cell proliferation & (D) decreased colony formation. Error bars represent mean ± SD of three replicates (*P < 0.05, **P < 0.01, ***P < 0.001). (E) A673 & SKNMC cells stably expressing shMEIS1 were transiently transfected with plasmid encoding APCDD1, & subjected to immunoblotting & MTT assays. Bars represent mean ± SD of three replicates (**P < 0.01). (F) Proposed model showing that MEIS1 & EWS-FLI1 co-operatively activate APCDD1 transcription, thereby promoting the malignant phenotype of Ewing sarcoma cells. Image collected & cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/30496486), licensed under a CC-BY license. Not internally tested by Novus Biologicals.](http://images.novusbio.com/fullsize/nb110-92756_rabbit-polyclonal-apcdd1-antibody-310202416205184.jpg)
![Western Blot: APCDD1 Antibody - BSA Free [NB110-92756] - APCDD1 is co-regulated by MEIS1 & EWS-FLI1 & mediates the oncogenic role of MEIS1. (A, B) Silencing of (A) MEIS1 or (B) EWS-FLI1 downregulated expression of both APCDD1 mRNA & protein. Error bars represent mean ± SD of three replicates (**P < 0.01, ***P < 0.001). (C, D) APCDD1 knockdown potently (C) inhibited cell proliferation & (D) decreased colony formation. Error bars represent mean ± SD of three replicates (*P < 0.05, **P < 0.01, ***P < 0.001). (E) A673 & SKNMC cells stably expressing shMEIS1 were transiently transfected with plasmid encoding APCDD1, & subjected to immunoblotting & MTT assays. Bars represent mean ± SD of three replicates (**P < 0.01). (F) Proposed model showing that MEIS1 & EWS-FLI1 co-operatively activate APCDD1 transcription, thereby promoting the malignant phenotype of Ewing sarcoma cells. Image collected & cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/30496486), licensed under a CC-BY license. Not internally tested by Novus Biologicals.](http://images.novusbio.com/fullsize/nb110-92756_rabbit-polyclonal-apcdd1-antibody-310202416212389.jpg)