Western blot shows lysates of HeLa human cervical epithelial carcinoma cell line. PVDF membrane was probed with 0.5 µg/mL of Human XPA Antigen Affinity‑purified Polyclonal Antibody (Catalog # AF3416) followed by ...read more
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Immunogen affinity purified
Reconstitute at 0.2 mg/mL in sterile PBS.
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for XPA Antibody
DNA repair protein complementing XP-A cells
Xeroderma pigmentosum group A-complementing protein
xeroderma pigmentosum, complementation group A
The Xeroderma Pigmentosum A (XPA) protein is a component of a large complex that binds to damaged DNA to facilitate nucleotide excision repair (NER). XPA binds in a complex with Replication Protein A (RPA), XPG, and TFIIH (a subcomplex of the RNA polymerase II transcription initiation complex). XPA is thought to stabilize the binding of RPA to DNA, and thus aid in specific recognition of the damaged base. Because of their NER defect, XP patients exhibit hypersensitivity to ultraviolet light and have a heightened incidence of skin cancer.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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