Product Details

Reactivity HuSpecies Glossary
Concentration is not relevant for this product. Please see the protocols for proper use of this product.

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XBP1 RNAi Summary

X-box binding protein 1 (XBP1), mRNA

Packaging, Storage & Formulations

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Concentration is not relevant for this product. Please see the protocols for proper use of this product.


This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for XBP1 RNAi

  • HTF
  • TREB5
  • X-box binding protein 1
  • X-box-binding protein 1
  • XBP-1
  • XBP2
  • XBP2Tax-responsive element-binding protein 5


Chimera RNA interference (chimera RNAi) is process by which small interfering RNA/DNA chimera triggers the destruction of mRNA for the original gene.  The discovery work, design, and application of chimera RNAi has been pioneered by Professor Kaoru Saigo and Dr. Kumiko Ui-Tei at the University of Tokyo.  Chimera RNAi has many advantages over the conventional siRNAs.  First, it has been demonstrated to have reliable knock-down for over 10,000 human genes.  Because the human genome is composed of an intricate, genetic network, chimera RNAi's unique design has successfully obviated the off-target effects including microRNA-based influence.  Another advantage of the chimera RNAi technology is its effectiveness at low concentrations (0.5nM to 5nM); only mRNA is destroyed so genomic genes are not affected.  Finally, having both the sense and anti-sense strands consisting RNA/DNA chimera, it offers much greater compound stability for streamlining in vitro and in vivo assays and applications while minimizing interferon induction and other adverse reactions.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. RNAi are guaranteed for 3 months from date of receipt.

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Publications for XBP1 RNAi (H00007494-R01) (0)

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Product General Protocols

View specific protocols for XBP1 RNAi (H00007494-R01): Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

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Blogs on XBP1.

Analysis of Total & pSer724 IRE1 alpha, the Sensor of ER Stress
Inositol-requiring protein 1/IRE1 alpha (also called Endoplasmic Reticulum to Nucleus Signaling 1/ERN1; predicted mol wt 110 kDa) is a serine-threonine protein kinase/endoribonuclease which plays a highly critical role in unfolded protein response/U...  Read full blog post.

IRE1 - an important sensor in the unfolded protein response pathway
During cellular stress the protein folding capacity of the ER is diminished. In order to maintain homeostasis and ensure proper protein folding cells activate the unfolded protein response (UPR), a signaling network consisting of sensors and effect...  Read full blog post.

Contact Information

Product PDFs


Gene Symbol XBP1

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