WHSC1 Antibody

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Western Blot: WHSC1 Antibody [NBP1-71849] - Whole cell lysate (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells. Affinity purified rabbit anti-NSD2 antibody used for WB at 0.04 mcg/ml (A) and ...read more

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-71849
    • Availability
      Product Discontinued

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WHSC1 Antibody Summary

Immunogen
The immunogen for this product maps to a region between residue 525 and 575 of human Nuclear SET Domain-Containing Protein 2 using the numbering given in entry NP_579877.1 (GeneID 7468).
Clonality
Polyclonal
Host
Rabbit
Gene
WHSC1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for WHSC1 Antibody

  • EC 2.1.1.43
  • FLJ23286
  • IL5 promoter REII region-binding protein
  • KIAA1090
  • MGC176638
  • MMSETNSD2Multiple myeloma SET domain-containing protein
  • multiple myeloma SET domain containing protein type III
  • Nuclear SET domain-containing protein 2
  • probable histone-lysine N-methyltransferase NSD2
  • Protein trithorax-5
  • REIIBP
  • trithorax/ash1-related protein 5
  • TRX5
  • WHS
  • Wolf-Hirschhorn syndrome candidate 1 protein
  • Wolf-Hirschhorn syndrome candidate 1

Background

This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

Additional WHSC1 Products

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Bioinformatics

Gene Symbol WHSC1
Uniprot