WDR3 Antibody

Western Blot: WDR3 Antibody [NB100-77296] - Detection of Human WDR3 on HeLa whole cell lysate using NB100-77296. WDR3 was also immunoprecipitated by another rabbit anti-WDR3 antibody.

• Reactivity: Hu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.2 mg/ml

WDR3 Antibody Summary

• Immunogen: The immunogen recognized by this antibody maps to a region between residue 225 and 275 of human WD repeat-containing domain 3 using the numbering given in entry NP_006775.1 (GeneID 10885).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: WDR3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 2-5 ug/mg lysate
  • Western Blot 1:2000-1:10000
• Theoretical MW: 106 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: TBS and 0.1% BSA
• Preservative: 0.09% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for WDR3 Antibody

• dJ776P7.2 (WD repeat domain 3)
• FLJ12796
• WD repeat domain 3
• WD repeat-containing protein 3

Background

This gene encodes a nuclear protein containing 10 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, which usually include a trp-asp at the C-terminal end. Proteins belonging to the WD repeat family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for WDR3 Antibody (NB100-77296)(1)

Publication using NB100-77296

• McMahon M, Ayllon V, Panov KI et al. Ribosomal 18 S RNA processing by the IGF-I-responsive WDR3 protein is integrated with p53 function in cancer cell proliferation. J Biol Chem 2010-06-01 [PMID: 20392698]

Bioinformatics

• Gene Symbol: WDR3
• Entrez:
  • 10885(Human)
• Uniprot:
  • Q9UNX4(Human)