VEGFR1/Flt-1 Antibody (RM0001-5F13) Summary
This antibody was produced from a hybridoma, mouse myeloma fused with spleen cells from a rat immunized with purified mouse VEGFR1 extracellular domain.
Endothelial Cell Marker
Recognizes mouse VEGFR1 in WB.
Protein G purified
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- Western Blot 1:500-1:1000
- Immunohistochemistry 1:50-1:100
- Immunohistochemistry-Paraffin 1:50-100
No crossreactivity to mouse VEGFR2 and VEGFR3.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
A 0.2 um filtered solution in PBS
Protein G purified
Reconstitute with 0.5 ml sterilized PBS to a final concentration of 0.2 mg/ml.
Alternate Names for VEGFR1/Flt-1 Antibody (RM0001-5F13)
- EC 2.7.10
- EC 184.108.40.206
- Fms-like tyrosine kinase 1
- fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascularpermeability factor receptor)
- Tyrosine-protein kinase FRT
- Tyrosine-protein kinase receptor FLT
- vascular endothelial growth factor receptor 1
- Vascular permeability factor receptor
- VEGF R1
VEGF Receptor 1 (also known as FLT) belongs to the src gene family and shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation. The protein acts as a receptor for VEGF, VEGFB and PGF. An alternatively spliced form of the gene produces a soluble protein (sFlt1) which binds vascular endothelial growth factor (VEGF) with high affinity. Because sFlt1 has a higher affinity for VEGF it may function as an inhibitor of VEGF response. VEGF Receptor 1 is specifically expressed in most vascular endothelial cells and peripheral blood monocytes.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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