VEGFR1/Flt-1 Antibody (RM0001-5F13)

Images

 
Immunohistochemistry-Paraffin: VEGF Receptor 1 Antibody (RM0001-5F13) [NB110-61016] - Paraffin lung section from LPS treated mice was subjected to IHC using anti VEGFR-1 antibody RM0001-5F13 (Righr Panel, Negative ...read more

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB110-61016
    • Availability
      Product Discontinued

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VEGFR1/Flt-1 Antibody (RM0001-5F13) Summary

Immunogen
This antibody was produced from a hybridoma, mouse myeloma fused with spleen cells from a rat immunized with purified mouse VEGFR1 extracellular domain.
Marker
Endothelial Cell Marker
Specificity
Recognizes mouse VEGFR1 in WB.
Isotype
IgG2
Clonality
Monoclonal
Host
Rat
Gene
FLT1
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
  • Immunohistochemistry 1:50-1:100
  • Immunohistochemistry-Paraffin 1:50-100

Reactivity Notes

No crossreactivity to mouse VEGFR2 and VEGFR3.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
A 0.2 um filtered solution in PBS
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein G purified
Reconstitution Instructions
Reconstitute with 0.5 ml sterilized PBS to a final concentration of 0.2 mg/ml.

Alternate Names for VEGFR1/Flt-1 Antibody (RM0001-5F13)

  • EC 2.7.10
  • EC 2.7.10.1
  • FLT
  • FLT1
  • Flt-1
  • Fms-like tyrosine kinase 1
  • fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascularpermeability factor receptor)
  • FRT
  • Tyrosine-protein kinase FRT
  • Tyrosine-protein kinase receptor FLT
  • vascular endothelial growth factor receptor 1
  • Vascular permeability factor receptor
  • VEGF R1
  • VEGFR1
  • VEGFR-1

Background

VEGF Receptor 1 (also known as FLT) belongs to the src gene family and shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation. The protein acts as a receptor for VEGF, VEGFB and PGF. An alternatively spliced form of the gene produces a soluble protein (sFlt1) which binds vascular endothelial growth factor (VEGF) with high affinity. Because sFlt1 has a higher affinity for VEGF it may function as an inhibitor of VEGF response. VEGF Receptor 1 is specifically expressed in most vascular endothelial cells and peripheral blood monocytes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

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Additional VEGFR1/Flt-1 Products

Bioinformatics Tool for VEGFR1/Flt-1 Antibody (NB110-61016)

Discover related pathways, diseases and genes to VEGFR1/Flt-1 Antibody (NB110-61016). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for VEGFR1/Flt-1 Antibody (NB110-61016)

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Pathways for VEGFR1/Flt-1 Antibody (NB110-61016)

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PTMs for VEGFR1/Flt-1 Antibody (NB110-61016)

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Bioinformatics

Gene Symbol FLT1
Entrez
Uniprot