VEGFR1/Flt-1 Antibody (Flt-1/EWC) [Biotin] Summary
Recombinant human soluble extracellular Flt-1 D1-D5 native protein.
Type I membrane protein (Flt1) and soluble (SFlt1).
Endothelial Cell Marker
The monoclonal will detect native and denaturated human VEGFR-1/ Flt-1 in ELISA experiments and on the surface of different human cell types. The will also detect mouse Flt-1.
Protein G purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Biotin (A=N/A, E=N/A)
Protein G purified
Reconstitute with 50 ul sterilized water to desired concetration.
Not yet tested in other species. Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.
Alternate Names for VEGFR1/Flt-1 Antibody (Flt-1/EWC) [Biotin]
- EC 2.7.10
- EC 220.127.116.11
- Fms-like tyrosine kinase 1
- fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascularpermeability factor receptor)
- Tyrosine-protein kinase FRT
- Tyrosine-protein kinase receptor FLT
- vascular endothelial growth factor receptor 1
- Vascular permeability factor receptor
VEGF Receptor 1 (also known as FLT) belongs to the src gene family and shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation. The protein acts as a receptor for VEGF, VEGFB and PGF. An alternatively spliced form of the gene produces a soluble protein (sFlt1) which binds vascular endothelial growth factor (VEGF) with high affinity. sFlt1 has a higher affinity for VEGF indicating that it may function as an inhibitor in the VEGF response. VEGF Receptor 1 is specifically expressed in most vascular endothelial cells and peripheral blood monocytes.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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