VEGFR1/Flt-1 Antibody (EIC) Summary
For immunization recombinant human soluble extracellular Flt-1 (D1-D5) native protein was used. The epitope is mapping at the amino terminus.
Type I membrane protein (Flt1) and soluble (SFlt1).
Endothelial Cell Marker
The monoclonal will detect native and denaturated human VEGFR-1/Flt-1 1 in ELISA experiments, immunocytochemistry and cell sorting.
Protein G purified
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Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS pH 7.4. Product is
Protein G purified
Reconstitute with 0.1 ml sterilized water to desired concentration.
analysis and cell sorting: The antibody has been used for the detection of Flt-1 positive cells (e.g. PAE/Flt-1 cells).
Not yet tested in other species.
Alternate Names for VEGFR1/Flt-1 Antibody (EIC)
- EC 2.7.10
- EC 18.104.22.168
- Fms-like tyrosine kinase 1
- fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascularpermeability factor receptor)
- Tyrosine-protein kinase FRT
- Tyrosine-protein kinase receptor FLT
- vascular endothelial growth factor receptor 1
- Vascular permeability factor receptor
VEGF and its high-affinity binding receptors, the tyrosine kinases FLK1 and FLT1, are thought to be important for the development of embryonic vasculature. It has been shown that an alternately spliced form of FLT1 produces a soluble protein, termed sFLT1, which binds vascular endothelial growth factor with high affinity. Because sFLT1 has a higher affinity for VEGF than does FLK1, it may function as an inhibitor of VEGF response.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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