VEGF165b Antibody (7F17)

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Product Details

Summary
Product Discontinued
View other related VEGF165b Primary Antibodies

Order Details


    • Catalog Number
      NBP1-18618
    • Availability
      Product Discontinued

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VEGF165b Antibody (7F17) Summary

Immunogen
recombinant human VEGF-165b C-terminal peptide
Specificity
VEGF165b (7F17)
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
VEGFA
Purity
Protein G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:1000
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:20-1:100

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
0.2 um filtered solution in PBS
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein G purified
Reconstitution Instructions
Reconstitute with 0.5 ml sterilized PBS to a final concentration of 0.2 mg/ml.

Alternate Names for VEGF165b Antibody (7F17)

  • MVCD1
  • vascular endothelial growth factor A
  • Vascular permeability factor
  • VEGF
  • VEGFA
  • VEGF-A
  • VEGFMGC70609
  • VPF
  • VPFvascular endothelial growth factor

Background

Angiogenesis, required for all tumor growth, is stimulated by the expression of vascular endothelial growth factor (VEGF). VEGF is up-regulated in all known solid tumors but also in atherosclerosis, diabetic retinopathy, arthritis, and many other conditions. Conventional VEGF isoforms have been universally described as proangiogenic cytokines. VEGF 165b, an endogenous splice variant, is expressed as protein in normal cells and tissues and is circulating in human plasma. VEGF 165b binds VEGF receptor 2 with the same affinity as VEGF 165 but does not activate it or stimulate downstream signaling pathways. Moreover, it prevents VEGF 165-mediated VEGF receptor 2 phosphorylation and signaling in cultured cells. VEGF 165b is not angiogenic and it inhibits VEGF 165-mediated angiogenesis in rabbit cornea and rat mesentery.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

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Bioinformatics Tool for VEGF165b Antibody (NBP1-18618)

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Diseases for VEGF165b Antibody (NBP1-18618)

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Bioinformatics

Gene Symbol VEGFA
Entrez