VEGF165b Antibody (7F17)



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VEGF165b Antibody (7F17) Summary

recombinant human VEGF-165b C-terminal peptide
VEGF165b (7F17)
Protein G purified
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Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.2 um filtered solution in PBS
No Preservative
LYOPH mg/ml
Protein G purified
Reconstitution Instructions
Reconstitute with 0.5 ml sterilized PBS to a final concentration of 0.2 mg/ml.

Reactivity Notes



Angiogenesis, required for all tumor growth, is stimulated by the expression of vascular endothelial growth factor (VEGF). VEGF is up-regulated in all known solid tumors but also in atherosclerosis, diabetic retinopathy, arthritis, and many other conditions. Conventional VEGF isoforms have been universally described as proangiogenic cytokines. VEGF 165b, an endogenous splice variant, is expressed as protein in normal cells and tissues and is circulating in human plasma. VEGF 165b binds VEGF receptor 2 with the same affinity as VEGF 165 but does not activate it or stimulate downstream signaling pathways. Moreover, it prevents VEGF 165-mediated VEGF receptor 2 phosphorylation and signaling in cultured cells. VEGF 165b is not angiogenic and it inhibits VEGF 165-mediated angiogenesis in rabbit cornea and rat mesentery.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product PDFs


Gene Symbol VEGFA

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