VEGF R2/KDR/Flk-1 Antibody (SP123)

Images

 
Immunohistochemistry-Paraffin: VEGF R2/KDR/Flk-1 Antibody (SP123) [NBP1-74520] - Human Bladder stained with anti-FLK-1 (mouse) antibody.
Immunohistochemistry-Paraffin: VEGF R2/KDR/Flk-1 Antibody (SP123) [NBP1-74520] - Human Placenta stained with anti-FLK-1 (mouse) antibody.
Immunohistochemistry-Paraffin: VEGF R2/KDR/Flk-1 Antibody (SP123) [NBP1-74520] - Human Prostate Adenocarcinoma stained with anti-FLK-1 (mouse) antibody.
Immunohistochemistry-Paraffin: VEGF R2/KDR/Flk-1 Antibody (SP123) [NBP1-74520] - Human Skin stained with anti-FLK-1 (mouse) antibody.
Immunohistochemistry-Paraffin: VEGF R2/KDR/Flk-1 Antibody (SP123) [NBP1-74520] - Human Breast Ductal Carcinoma stained with anti-FLK-1 (mouse) antibody.
Immunohistochemistry-Paraffin: VEGF R2/KDR/Flk-1 Antibody (SP123) [NBP1-74520] - Human Colon Adenocarcinoma stained with anti-FLK-1 (mouse) antibody.
Immunohistochemistry-Paraffin: VEGF R2/KDR/Flk-1 Antibody (SP123) [NBP1-74520] - Human B Cell Lymphoma stained with anti-FLK-1 (mouse) antibody.
Immunohistochemistry-Paraffin: VEGF R2/KDR/Flk-1 Antibody (SP123) [NBP1-74520] - Human Kidney stained with anti-FLK-1 (mouse) antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, IHC-P
Clone
SP123
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

VEGF R2/KDR/Flk-1 Antibody (SP123) Summary

Immunogen
Synthetic peptide near the N-terminus of mouse FLK-1 protein.
Marker
Endothelial Cell Marker
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
KDR
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:100
Theoretical MW
151.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.6) and 1.0% BSA
Preservative
0.1% Sodium Azide
Purity
Protein A purified

Alternate Names for VEGF R2/KDR/Flk-1 Antibody (SP123)

  • CD309 antigen
  • CD309
  • EC 2.7.10
  • EC 2.7.10.1
  • Fetal liver kinase 1
  • fetal liver kinase-1
  • Flk1
  • Flk-1
  • FLK1tyrosine kinase growth factor receptor
  • KDR
  • kinase insert domain receptor (a type III receptor tyrosine kinase)
  • Kinase insert domain receptor
  • Protein-tyrosine kinase receptor flk-1
  • soluble VEGFR2
  • vascular endothelial growth factor receptor 2
  • VEGF R2
  • VEGFR
  • VEGFR2
  • VEGFR-2

Background

FLK-1/KDR/VEGFR2, a cell membrane receptor kinase, is a high affinity receptor for vascular endothelial growth factor and is putatively involved in the growth of endothelial cells and angiogenesis. It contains seven immunoglobulin-like sequences in the extracellular domain and exhibits sequence similarity to FLT-1 and FLT-4.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Diseases for VEGF R2/KDR/Flk-1 Antibody (NBP1-74520)

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Blogs on VEGF R2/KDR/Flk-1.

HIF-3 alpha: a versatile target with hypoxia dependent and independent functions
By: Subhash GangarHIF-3 alpha (hypoxia-inducible factor 3-alpha/ HIF3A) represents an isoform of HIF-alpha subunits which heterodimerize with stable beta subunit (HIF-beta) for the regulation of HIF target genes through binding to hypoxia respon...  Read full blog post.

VEGFR-2 - A highly active kinase
VEGFR-2 is a family member of the vascular endothelial growth factor (VEGF) family of membrane receptor tyrosine kinases. It is a key regulator of the process of angiogenesis that takes place during fundamental developmental processes such as embry...  Read full blog post.

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Bioinformatics

Gene Symbol KDR
Entrez