VEGF R2/KDR/Flk-1 Antibody (KDR657) [DyLight 488]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Clone
KDR657
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 488

VEGF R2/KDR/Flk-1 Antibody (KDR657) [DyLight 488] Summary

Immunogen
Recombinant human VEGF-R2 protein
Localization
Cell surface
Marker
Hemangioblast Marker
Specificity
CD309, also known as VEGF-R2, KDR3, and Flk-1 (mouse), is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Human VEGF-R2 is mainly expressed by endothelial cells, embryonic tissues, and megakaryocytes. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGF-R2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGF-R2 with its ligands results in the receptor dimerization and auto-phosphorylation, stimulating endothelial cell proliferation and migration.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
KDR
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for VEGF R2/KDR/Flk-1 Antibody (KDR657) [DyLight 488]

  • CD309 antigen
  • CD309
  • EC 2.7.10
  • EC 2.7.10.1
  • Fetal liver kinase 1
  • fetal liver kinase-1
  • Flk1
  • Flk-1
  • FLK1tyrosine kinase growth factor receptor
  • KDR
  • kinase insert domain receptor (a type III receptor tyrosine kinase)
  • Kinase insert domain receptor
  • Protein-tyrosine kinase receptor flk-1
  • soluble VEGFR2
  • vascular endothelial growth factor receptor 2
  • VEGF R2
  • VEGFR
  • VEGFR2
  • VEGFR-2

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics Tool for VEGF R2/KDR/Flk-1 Antibody (NBP2-34657G)

Discover related pathways, diseases and genes to VEGF R2/KDR/Flk-1 Antibody (NBP2-34657G). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for VEGF R2/KDR/Flk-1 Antibody (NBP2-34657G)

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PTMs for VEGF R2/KDR/Flk-1 Antibody (NBP2-34657G)

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Research Areas for VEGF R2/KDR/Flk-1 Antibody (NBP2-34657G)

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Blogs on VEGF R2/KDR/Flk-1.

HIF-3 alpha: a versatile target with hypoxia dependent and independent functions
By: Subhash GangarHIF-3 alpha (hypoxia-inducible factor 3-alpha/ HIF3A) represents an isoform of HIF-alpha subunits which heterodimerize with stable beta subunit (HIF-beta) for the regulation of HIF target genes through binding to hypoxia respon...  Read full blog post.

VEGFR-2 - A highly active kinase
VEGFR-2 is a family member of the vascular endothelial growth factor (VEGF) family of membrane receptor tyrosine kinases. It is a key regulator of the process of angiogenesis that takes place during fundamental developmental processes such as embry...  Read full blog post.

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Bioinformatics

Gene Symbol KDR
Entrez