VEGF-C Antibody

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Western Blot: VEGFC Antibody [NBP1-45924] - Analysis with recombinant human VEGF-c.

Product Details

Summary
Product Discontinued
View other related VEGF-C Primary Antibodies

Order Details


    • Catalog Number
      NBP1-45924
    • Availability
      Product Discontinued

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VEGF-C Antibody Summary

Immunogen
E. coli-expressed recombinant human VEGF-C.
Clonality
Polyclonal
Host
Rabbit
Gene
VEGFC
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Immunohistochemistry
Application Notes
Western blotting (0.5-4 ug/ml) and Immunohistochemistry (5 ug/ml). However, the optimal concentrations should be determined individually. Reactivity to other species has not been tested.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2), 0.5% BSA and 30% Glycerol
Preservative
0.01% Thimerosal
Purity
Immunogen affinity purified

Alternate Names for VEGF-C Antibody

  • Flt4 ligand
  • Flt4-L
  • vascular endothelial growth factor C
  • Vascular endothelial growth factor-related protein
  • VEGFC
  • VEGF-C
  • VRPFLT4 ligand DHM

Background

Vascular endothelial growth factors (VEGFs), also known as vasculotropins, are a family of closely related growth factors having a conserved pattern of eight cysteine residues and sharing common VEGF receptors. VEGFs stimulate the proliferation of endothelial cells, induce angiogenesis, promote cell migration, increase vascular permeability, and inhibit apoptosis. The mitogenic activity of VEGFs appears to be mediated by specific VEGF receptors. The target cell specificity of VEGF is restricted to vascular endothelial cells. Vascular Endothelial Growth Factor C (VEGFC) is a member of the VEGF subfamily of PDGF-related growth factors. It is the ligand for Flt4 (VEGFR3) and KDR (VEGFR2). VEGFC binds Flt4 and induces tyrosine autophosphorylation of VEGFR3 and VEGFR2. VEGFC also stimulates the migration of bovine capillary endothelial cells in collagen gel. It is a specific growth factor for the lymphatic vascular system and mediates lymphangiogenesis. VEGFC is abundantly expressed in heart and skeletal muscle. Other tissues such as lung and kidney also express VEGFC. The human VEGFC gene is located on chromosome 4q34.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for VEGF-C Antibody (NBP1-45924). (Showing 1 - 1 of 1 FAQ).

  1. I was wondering if you know of any blocking antibodies against IL-6 or VEGF-C that can be used in cell culture to quench these cytokines?
    • We have no antibodies that are currently known to show blocking antibodies to VEGF-C. Please see this link to our IL-6 antibodies with blocking/neutralizing activity can be found at this link.

Secondary Antibodies

 

Isotype Controls

Additional VEGF-C Products

Bioinformatics Tool for VEGF-C Antibody (NBP1-45924)

Discover related pathways, diseases and genes to VEGF-C Antibody (NBP1-45924). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for VEGF-C Antibody (NBP1-45924)

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Pathways for VEGF-C Antibody (NBP1-45924)

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PTMs for VEGF-C Antibody (NBP1-45924)

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Research Areas for VEGF-C Antibody (NBP1-45924)

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Blogs on VEGF-C

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Contact Information

Product PDFs

Calculators

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Bioinformatics

Gene Symbol VEGFC
Entrez
Uniprot