Recombinant Human VEGF-B Protein Summary
A bioactive recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 22-207 of Human VEGF-B
Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MPVSQPDAPG HQRKVVSWID VYTRATCQPR EVVVPLTVEL MGTVAKQLVP SCVTVQRCGG CCPDDGLECV PTGQHQVRMQ ILMIRYPSSQ LGEMSLEEHS QCECRPKKKD SAVKPDRAAT PHHRPQPRSV PGWDSAPGAP SPADITHPTP APGPSAHAAP STTSALTPGP AAAAADAAAS SVAKGGA
|Details of Functionality
Measured in a cell proliferation assay using NIH-3T3 mouse
embryonic fibroblast. The ED50 for this effect is < 1ng/ml.
| Protein/Peptide Type
Biologically Active Protein
>90%, by SDS-PAGE
< 1.0 EU per 1 microgram of protein (determined by LAL method)
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
20 mM Tris-HCl buffer (pH 7.5) containing 10% glycerol
>90%, by SDS-PAGE
Alternate Names for Recombinant Human VEGF-B Protein
- vascular endothelial growth factor B
- VEGF-related factor
VEGF-B, also known as Vascular endothelial growth factor-B, is one of 5 mammalian VEGF family members, the others being VEGF-A, VEGF-C, VEGF-D, and placental growth factor (PlGF). VEGF-B binds to one of the VEGF receptor tyrosine kinases, namely VEGF receptor-1(VEGFR1, Flt1), but not to VEGFR2 and VEGFR3. VEGF-B is homodimeric, heparin-binding glycoprotein involved in embryonic angiogenesis and vasculogenesis. Recombinant VEGF-B protein was expressed in E.coli and purified by using conventional chromatography techniques.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed
for 2 years from date of receipt.
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