VCAM-1/CD106 Antibody (STA)

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Product Details

Summary
Product Discontinued
View other related VCAM-1/CD106 Primary Antibodies

Order Details


    • Catalog Number
      NBP1-42790
    • Availability
      Product Discontinued

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VCAM-1/CD106 Antibody (STA) Summary

Immunogen
Human DS6 T cell line
Specificity
The mouse monoclonal antibody STA recognizes CD106 antigen (VCAM-1), a 100-110 kDa type I membrane protein of the immunoglobulin superfamily, a crucial mediator of leukocyte adhesion, and a costimulation molecule. HLDA V; WS Code A013
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
VCAM1
Purity
Protein A purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA 1:2000
  • Flow Cytometry 4 - 6 ug/ml
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:200
  • Immunoprecipitation 1:50
  • CyTOF-ready
Application Notes
Immunohistochemistry-Frozen sections: acetone fixation recommended ELISA: Capture mAb for soluble CD106

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.4)
Preservative
15mM Sodium Azide
Concentration
1 mg/ml
Purity
Protein A purified

Alternate Names for VCAM-1/CD106 Antibody (STA)

  • CD106 antigen
  • CD106
  • DKFZp779G2333
  • INCAM-100
  • L1CAM
  • MGC99561
  • vascular cell adhesion molecule 1
  • vascular cell adhesion protein 1
  • V-CAM 1
  • VCAM1
  • VCAM-1

Background

CD106 / VCAM-1 (vascular cell adhesion molecule-1) is an Ig-like cell surface adhesion molecule binding VLA-4 integrin. VCAM-1 is a potent T cell costimulatory molecule taking part in their positive selection and survival, as well as in adhesion, transendothelial migration and activation of peripheral T cells. VCAM-1 is also involved in endothelial cell-cell contacts. Whereas VCAM-1 normally mediates leukocyte extravasion to sites of tissue inflammation, tumour cells can use overexpressed VCAM-1 to escape T cell immunity. Soluble form of VCAM-1 (sVCAM-1) is an inflammatory marker and can be used also in prognosis of subsequent cariovascular events following acute coronary syndromes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Additional VCAM-1/CD106 Products

Bioinformatics Tool for VCAM-1/CD106 Antibody (NBP1-42790)

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Diseases for VCAM-1/CD106 Antibody (NBP1-42790)

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PTMs for VCAM-1/CD106 Antibody (NBP1-42790)

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Bioinformatics

Gene Symbol VCAM1
Entrez