VCAM-1/CD106 Antibody (STA) Summary
Human DS6 T cell line
The mouse monoclonal antibody STA recognizes CD106 antigen (VCAM-1), a 100-110 kDa type I membrane protein of the immunoglobulin superfamily, a crucial mediator of leukocyte adhesion, and a costimulation molecule. HLDA V; WS Code A013
Protein A purified
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- ELISA 1:2000
- Flow Cytometry 4 - 6 ug/ml
- Immunohistochemistry 1:10-1:500
- Immunohistochemistry-Frozen 1:200
- Immunoprecipitation 1:50
Immunohistochemistry-Frozen sections: acetone fixation recommended ELISA: Capture mAb for soluble CD106
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
PBS (pH 7.4)
15mM Sodium Azide
Protein A purified
Alternate Names for VCAM-1/CD106 Antibody (STA)
- CD106 antigen
- vascular cell adhesion molecule 1
- vascular cell adhesion protein 1
- V-CAM 1
CD106 / VCAM-1 (vascular cell adhesion molecule-1) is an Ig-like cell surface adhesion molecule binding VLA-4 integrin. VCAM-1 is a potent T cell costimulatory molecule taking part in their positive selection and survival, as well as in adhesion, transendothelial migration and activation of peripheral T cells. VCAM-1 is also involved in endothelial cell-cell contacts. Whereas VCAM-1 normally mediates leukocyte extravasion to sites of tissue inflammation, tumour cells can use overexpressed VCAM-1 to escape T cell immunity. Soluble form of VCAM-1 (sVCAM-1) is an inflammatory marker and can be used also in prognosis of subsequent cariovascular events following acute coronary syndromes.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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