VAV2 Antibody


Western Blot: VAV2 Antibody [NBP1-19661] Extracts from THP1 cells.
Western Blot: VAV2 Antibody [NBP1-19661] - (WB) analysis of VAV2 (D138) antibody in extracts from NIH cells.

Product Details

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VAV2 Antibody Summary

Synthetic peptide, corresponding to amino acids 100-150 of Human VAV2.
Immunogen affinity purified
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  • Western Blot 1:500-1:1000
  • Immunocytochemistry/Immunofluorescence 1:50-1:200
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:50-1:200
Application Notes
Western blot (WB) analysis of VAV2 (D138) pAb in extracts from THP1 cells.
Theoretical MW
108 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Cross reacts with Human and Mouse.

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.2)
15mM Sodium Azide
1.0 mg/ml
Immunogen affinity purified

Alternate Names for VAV2 Antibody

  • guanine nucleotide exchange factor VAV2
  • oncogene VAV2
  • Protein vav-2
  • vav 2 guanine nucleotide exchange factor
  • vav 2 oncogene
  • VAV-2


VAV2 is a ubiquitously expressed structural homolog of the VAV protooncogene that is expressed preferentially in hematopoetic cells. Both proteins are comprised of a Dbl homology (DH) domain with guanosine nucleotide exchange (GEF) activity exclusively directed towards Rho/Rac GTPases, a pleckstrin homology (PH) domain, a calponin-homology (CH) region, an acidic domain (AD) a zinc finger butterfly motif, two SH3 regions and one SH2 domain. GEF activity of RhoA family G proteins is induced by tyrosine phosphorylation in wild type VAV2, and is constitutively activated in N terminus deleted oncogene forms. Constitutive expression of a VAV2 oncoprotein may result in morphological alterations including highly enlarged cells in which karyokinesis and cytokinesis frequently are uncoupled.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Gene Symbol VAV2