Vav-1 [p Tyr174] Antibody


Western Blot: Vav-1 Antibody [NBP1-51428] - Analyzes of p-Vav1 (Y174) pAb in extracts from Jurkat UV cells.

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Vav-1 [p Tyr174] Antibody Summary

Synthetic phosphopeptide derived from human Vav1 around the phosphorylation site of Tyrosine 174.
p Tyr174
p-Vav1 (Y174) pAb detects endogenous levels of Vav1 protein only when phosphorylated at Y174.
Immunogen affinity purified
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  • Western Blot 1:500-1:1000
Application Notes
Western blot (WB) analyzes of p-Vav1 (Y174) pAb in extracts from Jurkat UV cells.
Theoretical MW
100 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human, Mouse, Rat

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.2)
0.05% Sodium Azide
1.0 mg/ml
Immunogen affinity purified

Alternate Names for Vav-1 [p Tyr174] Antibody

  • oncogene vav
  • proto-oncogene vav
  • vav 1 guanine nucleotide exchange factor
  • vav proto-oncogene
  • Vav1
  • Vav-1
  • vav-T
  • VAVvav 1 oncogene


The Vav gene was originally identified on the basis of its oncogenic activation during the course of gene transfer assays. The major translational product of the Vav proto-oncogene has been identified as a protein containing an array of structural motifs. Contained within its amino terminus are a helix-loop-helix domain and a leucine zipper motif similar to that of Myc family proteins; deletion of this region of p95Vav causes its oncogenic activation. In addition, p95Vav contains an SH2 domain, which could indicate its role as a substrate for tyrosine kinases. Expression of p95Vav is limited exclusively to cells of hematopoietic origin, including those of the erythroid, lymphoid and myeloid lineages. These results suggest that p95Vav may represent a new type of signal transduction molecule involved in the transduction of tyrosine phosphorylation signaling into transcriptional events.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Gene Symbol VAV1