Vanin-1/VNN1 Overexpression Lysate (Denatured)

Product Discontinued

Vanin-1/VNN1 Overexpression Lysate (Denatured) Summary

• Description: Quality control test: Transient overexpression cell lysate was tested with Anti-VNN1 antibody by Western Blots. Plasmid: pCMV-VNN1 full-length
• Gene: VNN1

Applications/Dilutions

• Dilutions:
  • Western Blot

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 22720042).

Packaging, Storage & Formulations

• Storage: Store at -80C. Avoid freeze-thaw cycles.
• Buffer: Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, and 0.01% Bromophenol blue).

Lysate Details for Array

• Type: Overexpression
• Protein State: Denatured

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Vanin-1/VNN1 Overexpression Lysate (Denatured)

• EC 3.5.1
• EC 3.5.1.92
• HDLCQ8
• MGC116930
• MGC116931
• MGC116932
• Pantetheinase
• Pantetheine hydrolase
• Tiff66
• Tiff66MGC116933
• vanin 1
• Vanin1
• Vanin-1
• vannin 1
• Vascular non-inflammatory molecule 1
• VNN1

Background

This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

Publications for Vanin-1/VNN1 Lysate (H00008876-T01)(1)

Publication using H00008876-T01

• Dammanahalli KJ, Stevens S, Terkeltaub R. et al. Vanin-1 pantetheinase drives smooth muscle cell activation in post-arterial injury neointimal hyperplasia. PLoS One 2012-06-13 [PMID: 22720042] (Mouse)

Bioinformatics

• Gene Symbol: VNN1