URI Overexpression Lysate (Denatured)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB

Order Details

URI Overexpression Lysate (Denatured) Summary

Description
Pasmid: pCMV-C19orf2 full-length
Gene
URI1

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, and 0.01% Bromophenol blue).

Lysate Details for URI

Type
Overexpression
Protein State
Denatured

Notes

Quality control test: Transient overexpression cell lysate was tested with Anti-C19orf2 antibody by Western Blots.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for URI Overexpression Lysate (Denatured)

  • chromosome 19 open reading frame 2
  • FLJ10575
  • NNX3RPB5-mediating protein
  • Protein NNX3
  • RMPunconventional prefoldin RPB5 interactor
  • RNA polymerase II subunit 5-mediating protein
  • URIRNA polymerase II, subunit 5-mediating protein

Background

The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its binding to RPB5. The encoded protein seems to have inhibitory effects on various types of activated transcription, but it requires the RPB5-binding region. This protein acts as a corepressor. It is suggested that it may require signaling processes for its function or that it negatively modulates genes in the chromatin structure. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Transcript Variant: This variant (2) lacks 35 nt in the coding region, resulting in a frameshift at the 5' end, compared to variant 1. It encodes an isoform b that is shorter and has a different N-terminus than isoform a.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

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Video Protocols

WB Video Protocol

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Bioinformatics

Gene Symbol URI1