UBE2N/Ubc13 Antibody

Images

 
Immunohistochemistry-Paraffin: UBE2N/Ubc13 Antibody [NBP1-02444] - Staining of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration ...read more
Immunohistochemistry-Paraffin: UBE2N/Ubc13 Antibody [NBP1-02444] - UBE2N antibody (2.5 ug/ml) was used in IHC to stain formalin-fixed, paraffin-embedded human thyroid, followed by biotinylated horse anti-goat IgG ...read more

Product Details

Summary
Reactivity Hu, Mu, Rt, Bv, Ca, Ch, Pm, Xp, ZeSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

UBE2N/Ubc13 Antibody Summary

Immunogen
Synthetic peptide from human UBE2N.
Specificity
Amino acids 40-51 of human UBC13 protein.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
UBE2N
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:2000
  • ELISA 1:5000-1:25000
  • Immunocytochemistry/Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 2.5 ug/ml

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Potassium Phosphate (pH 7.2) and 0.15M NaCl
Preservative
0.01% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for UBE2N/Ubc13 Antibody

  • bendless-like ubiquitin conjugating enzyme
  • Bendless-like ubiquitin-conjugating enzyme
  • BLU
  • EC 6.3.2.19
  • MGC131857
  • MGC8489
  • UBC13
  • UbcH13
  • UbcH-ben
  • UBE2N
  • Ubiquitin carrier protein N
  • ubiquitin-conjugating enzyme E2 N
  • ubiquitin-conjugating enzyme E2N (homologous to yeast UBC13)
  • ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)
  • Ubiquitin-protein ligase N
  • yeast UBC13 homolog

Background

UBC13 is a member of the E2 ubiquitin-conjugating enzyme family also known as Ubiquitin-conjugating enzyme E2 N, Ubiquitin-protein ligase N, Ubiquitin carrier protein N and Bendless-like ubiquitin-conjugating enzyme. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. UBC13 forms a heterodimer with UBE2V2 which then catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through Lys-63. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. UBC13 also mediates transcriptional activation of target genes and plays a role in the control of progress through the cell cycle and differentiation, as well as error-free DNA repair. UBC13 also contributes to the survival of cells after DNA damage.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NB100-56360
Species: Hu
Applications: WB
NBP1-89522
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NB100-56397
Species: Hu
Applications: WB
NBP2-26506
Species: Hu, Mu, Rt
NBP1-31302
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NBP1-89150
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
H00011026-M01
Species: Hu
Applications: WB, ELISA
NB500-106
Species: Hu, Mu, Rt, Po, Ch, Dr, Fi, Pm, Rb, Ye, Ze
Applications: WB, Simple Western, ChIP, ELISA, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, IHC-FrFl
NBP2-03644
Species: Hu
Applications: WB, Flow, ICC/IF, IHC, IHC-P
NBP2-29323
Species: Hu, Mu, Rt, Bv, Ca, Ch, Xp
H00009025-B01P
Species: Hu
Applications: WB, ICC/IF
NB100-304
Species: Hu, Mu, Rt, Fi, Gt, Pm
Applications: WB, ChIP, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, KO
NB100-598
Species: Hu
Applications: WB, Flow, ICC/IF, IP, CyTOF-ready
NB100-56363
Species: Hu, Mu
Applications: WB
NB100-56715
Species: Hu
Applications: WB, IHC, IHC-P
NBP1-89958
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P

Publications for UBE2N/Ubc13 Antibody (NBP1-02444) (0)

There are no publications for UBE2N/Ubc13 Antibody (NBP1-02444).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for UBE2N/Ubc13 Antibody (NBP1-02444) (0)

There are no reviews for UBE2N/Ubc13 Antibody (NBP1-02444). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for UBE2N/Ubc13 Antibody (NBP1-02444) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional UBE2N/Ubc13 Products

Bioinformatics Tool for UBE2N/Ubc13 Antibody (NBP1-02444)

Discover related pathways, diseases and genes to UBE2N/Ubc13 Antibody (NBP1-02444). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for UBE2N/Ubc13 Antibody (NBP1-02444)

Discover more about diseases related to UBE2N/Ubc13 Antibody (NBP1-02444).
 

Pathways for UBE2N/Ubc13 Antibody (NBP1-02444)

View related products by pathway.

PTMs for UBE2N/Ubc13 Antibody (NBP1-02444)

Learn more about PTMs related to UBE2N/Ubc13 Antibody (NBP1-02444).
 

Research Areas for UBE2N/Ubc13 Antibody (NBP1-02444)

Find related products by research area.

Blogs on UBE2N/Ubc13

There are no specific blogs for UBE2N/Ubc13, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our UBE2N/Ubc13 Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol UBE2N
Entrez
Uniprot