UbcH2/UBE2H Recombinant Protein


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Product Details

Reactivity HuSpecies Glossary
1 mg/ml

Order Details

UbcH2/UBE2H Recombinant Protein Summary

A recombinant protein corresponding to Human UbcH2/UBE2H

Source: E. coli

Amino Acid Sequence: The amino acid sequence of this product is not available.
E. coli

Packaging, Storage & Formulations

Store at -80C. Avoid freeze-thaw cycles.
Supplied at a concentration of 1.0 mg/ml in 20 mM Tris-HCl, pH 7.5, containing 0.5 mM DTT.
1 mg/ml


The purity of this protein is >95% pure by SDS-PAGE

Alternate Names for UbcH2/UBE2H Recombinant Protein

  • E2-14K
  • E2-20K
  • EC
  • UBC8
  • UBC8E2-20K
  • UBCH
  • UBCH2
  • UBE2H
  • Ubiquitin carrier protein H
  • ubiquitin-conjugating enzyme E2 H
  • Ubiquitin-conjugating enzyme E2-20K
  • ubiquitin-conjugating enzyme E2H (homologous to yeast UBC8)
  • ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)
  • Ubiquitin-protein ligase H


UbcH2 is the human homolog to the yeast DNA repair gene RAD6, which is induced by DNA damaging reagents. It has been shown to conjugate ubiquitin to histone H2A in an E3 dependent manner in vitro. UbcH2 consists of two functionally independent domains, an N-terminal core domain with ubiquitin conjugating activity, and a C-terminal domain that interacts with substrate proteins. This protein is useful for in vitro ubiquitinylation reactions. The His-tagged version of this enzyme is not susceptible to self-ubiquitinylation, which can occur with GST-tagged versions. Typical enzyme concentration to support conjugation in vitro is 100 nM to 1 uM depending upon conditions.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Contact Information

Product PDFs


Gene Symbol UBE2H

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