Tyrosinase Antibody

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Product Details

Summary
Product Discontinued
View other related Tyrosinase Primary Antibodies

Order Details


    • Catalog Number
      NB100-65507
    • Availability
      Product Discontinued

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Tyrosinase Antibody Summary

Immunogen
Highly pure tyrosinase from mushrooms.
Localization
Melanosomal membrane; single pass type I membrane protein.
Specificity
NB100-65507 is specific for mushroom Tyrosinase. In a simple ELISA with 1 microgram of antigen coated per well, the 50% OD was observed at 1/20,000. Under the same conditions, the end point was observed at 1/400,000.
Isotype
IgG
Clonality
Polyclonal
Host
Sheep
Gene
TYR
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000

Reactivity Notes

Fungi. Not yet tested in other species.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Whole antisera
Preservative
0.09% Sodium Azide
Purity
Unpurified

Alternate Names for Tyrosinase Antibody

  • CMM8
  • EC 1.14.18.1
  • LB24-AB
  • Monophenol monooxygenase
  • OCA1A
  • OCAIA
  • SHEP3
  • SK29-AB
  • Tumor rejection antigen AB
  • tyrosinase (oculocutaneous albinism IA)
  • tyrosinase

Background

Tyrosinase is a copper containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway. It is thought to catalyze the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6-dihydroxyindole to indole-5,6 quinone. A mutant allele of TYR is a common cause of autosomal recessive ocular albinism, also known as tyrosinase negative oculocutaneous albinism. This is an autosomal recessive disorder characterized by absence of pigment in hair, skin and eyes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics Tool for Tyrosinase Antibody (NB100-65507)

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Bioinformatics

Gene Symbol TYR