TXNRD2 Antibody - Pre-diluted

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Immunohistochemistry-Paraffin: TXNRD2 Antibody - Pre-diluted [NBP1-36578] - Human Liver Carcinoma stained with anti-Thioredoxin Reductase 2 (TrxR2) antibody.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-36578
    • Availability
      Product Discontinued

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TXNRD2 Antibody - Pre-diluted Summary

Immunogen
A synthetic peptide from C-terminus of human TrxR2.
Specificity
This product is specific for Thioredoxin Reductase 2 (TrxR2)
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TXNRD2
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin Neat

Reactivity Notes

Predicted by homology: Bovine, Frog, Mouse, Porcine, Rabbit, Rat.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Prediluted antibody with 50mM Tris (pH 7.7) and 1.0% BSA
Preservative
0.1% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for TXNRD2 Antibody - Pre-diluted

  • EC 1.8.1
  • EC 1.8.1.9
  • KIAA1652
  • Selenoprotein Z
  • SelZ
  • Thioredoxin Reductase 2
  • thioredoxin reductase 3
  • thioredoxin reductase beta
  • Thioredoxin reductase TR3
  • TR
  • TR3
  • TR-beta
  • TRXR2
  • TRXR2thioredoxin reductase 2, mitochondrial
  • TXNRD2

Background

The reduced form of thioredoxin serves as a hydrogen donor, contributes to the up-regulation of various transcription factors and binds to and inhibits MAPKKK activity. Oxidized thioredoxin is converted back to the reduced form by Thioredoxin Reductase (TrxR2), a redox active enzyme. There are two distinct isoforms in mammalian cells, TrxR1, a cytosolic protein and TrxR2, almost exclusively a mitochondrial protein. TrxR expression is induced in several tumors.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol TXNRD2
Entrez