TTF1 / NKX2.1 Antibody (SPM150) [DyLight 680]

Images

 
There are currently no images for TTF1 / NKX2.1 Antibody (NBP2-34742FR).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, Flow, ICC/IF, IHC-Fr, IHC-P
Clone
SPM150
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 680

TTF1 / NKX2.1 Antibody (SPM150) [DyLight 680] Summary

Immunogen
Rat full length TTF-1 recombinant protein
Localization
Nuclear
Marker
Thyroid & Lung Epithelial Marker
Specificity
Recognizes a protein of 40kDa, identified as Thyroid transcription factor-1 (TTF-1). TTF-1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. Anti-TTF-1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates.Loss of TTF-1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. TTF-1 reactivity is also seen in thyroid malignancies.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
NKX2-1
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
Theoretical MW
40 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Shows broad species reactivity.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Alternate Names for TTF1 / NKX2.1 Antibody (SPM150) [DyLight 680]

  • BCH
  • benign chorea
  • BHC
  • Homeobox protein NK-2 homolog A
  • homeobox protein Nkx-2.1
  • NK2 homeobox 1
  • NK-2 homolog A
  • NKX2.1
  • NKX2-1
  • NKX2A
  • NKX2ANKX2.1
  • T/EBP
  • Thyroid nuclear factor 1
  • Thyroid transcription factor 1BHC
  • TITF1
  • TITF1TEBP
  • TTF1
  • TTF-1
  • TTF1BCH
  • TTF-1NK-2

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP2-34294
Species: Hu, Mu, Rt
Applications: WB, Flow, IHC-P
H00054474-M01
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
NB300-187
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC
NBP1-88080
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC, IHC-P
NBP1-57977
Species: Hu
Applications: WB, IHC
NBP1-50811
Species: Hu
Applications: WB, ELISA, IA, S-ELISA
NBP1-32440
Species: Hu, Mu, Rt
Applications: WB, Simple Western, ChIP, ICC/IF, IHC, IHC-P, IP
NBP1-87201
Species: Hu
Applications: WB, IHC, IHC-P
NBP1-26642
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P, IP
AF1916
Species: Hu
Applications: WB, IHC, ICC
AF1095
Species: Hu
Applications: WB, Simple Western, IHC, CyTOF-ready, ICC, ICFlow
MAB4218
Species: Hu
Applications: WB, IHC
AF4077
Species: Hu
Applications: WB
NB100-1271
Species: Hu
Applications: IHC, IHC-P, PEP-ELISA
NBP1-19788
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P
NB100-355
Species: Hu, Mu, Rt, Po, Bv, Ca, Ch, Xp
Applications: WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, CyTOF-ready
NBP2-24482
Species: Hu, Mu, Rt, Ca, Ch, Pm
Applications: WB
MAB6534
Species: Hu
Applications: WB
NB300-653
Species: Hu, Mu, Rt, Ch, Mk
Applications: WB, ICC/IF, IHC, IHC-P, IP
NBP2-45677
Species: Hu, Mk
Applications: WB, IHC

Publications for TTF1 / NKX2.1 Antibody (NBP2-34742FR) (0)

There are no publications for TTF1 / NKX2.1 Antibody (NBP2-34742FR).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for TTF1 / NKX2.1 Antibody (NBP2-34742FR) (0)

There are no reviews for TTF1 / NKX2.1 Antibody (NBP2-34742FR). By submitting a review earn points towards our Rewards Program.
  • 250 points for product review
  • 500 additional points for an image with your product review
  • Double points (500) if you are the first to review this product
  • Double points (1000) if you are the first to review this product with an image

Product General Protocols

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for TTF1 / NKX2.1 Antibody (NBP2-34742FR) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional TTF1 / NKX2.1 Products

Related Products by Gene

Bioinformatics Tool for TTF1 / NKX2.1 Antibody (NBP2-34742FR)

Discover related pathways, diseases and genes to TTF1 / NKX2.1 Antibody (NBP2-34742FR). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for TTF1 / NKX2.1 Antibody (NBP2-34742FR)

Discover more about diseases related to TTF1 / NKX2.1 Antibody (NBP2-34742FR).
 

Pathways for TTF1 / NKX2.1 Antibody (NBP2-34742FR)

View related products by pathway.

PTMs for TTF1 / NKX2.1 Antibody (NBP2-34742FR)

Learn more about PTMs related to TTF1 / NKX2.1 Antibody (NBP2-34742FR).
 

Research Areas for TTF1 / NKX2.1 Antibody (NBP2-34742FR)

Find related products by research area.

Blogs on TTF1 / NKX2.1.

TTF1 / NKX2.1 - An essential regulator of lung development with implications in cancer diagnostics
Thyroid transcription factor 1 (TTF-1), also known as NKX2.1, is a conserved master regulatory transcription factor involved in the development of the lung, brain, and thyroid (1). In the lung TTF-1 positively regulates the expression of several lu...  Read full blog post.

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our TTF1 / NKX2.1 Antibody (SPM150) [DyLight 680] and receive a gift card or discount.

Bioinformatics

Gene Symbol NKX2-1
Entrez

Customers Who Bought This Also Bought