Recombinant Human TTC11 Protein

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SDS-Page: TTC11 Protein [NBP1-44386] - TTC11, 16.3 kDa(142aa), confirmed by MALDI-TOF with a purity of 95% by SDS - PAGE

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
1.0 mg/ml

Order Details

Recombinant Human TTC11 Protein Summary

Description
A recombinant protein with a His tag and corresponding to amino acids 1 - 122 of FIS1.

Source: E. coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MEAVLNELVS VEDLLKFEKK FQSEKAAGSV SKSTQFEYAW CLVRSKYNDD IRKGIVLLEE LLPKGSKEEQ RDYVFYLAVG NYRLKEYEKA LKYVRGLLQT EPQNNQAKEL ERLIDKAMKK DG

Preparation
Method
E.coli
Protein/Peptide Type
Recombinant Protein
Gene
FIS1
Purity
>95% pure by SDS-PAGE

Applications/Dilutions

Theoretical MW
16.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

This is a Human protein

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
20 mM Tris-HCl Buffer (pH 8.0) containing 10% glycerol
Preservative
No Preservative
Concentration
1.0 mg/ml
Purity
>95% pure by SDS-PAGE

Notes

The purity of this protein is > 95% by SDS-PAGE. Molecular weight is 16.3 kDa(142aa), confirmed by MALDI-TOF

Alternate Names for Recombinant Human TTC11 Protein

  • CGI-135
  • FIS1 homolog
  • Fis1
  • fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
  • fission 1 (mitochondrial outer membrane) homolog (yeast)
  • H_NH0132A01.6
  • hFis1
  • mitochondrial fission 1 protein
  • tetratricopeptide repeat domain 11
  • Tetratricopeptide repeat protein 11
  • TTC11TPR repeat protein 11

Background

TTC11 is a component of a mitochondrial complex that promotes mitochondrial fission. This protein can induce cytochrome C release from the mitochondrion to the cytosol, ultimately leading to apoptosis. It is also involved in peroxisomal growth and division. The C terminus is required for mitochondrial localisation, while the N teminus is necessary for mitochondrial fission. Recombinant human TTC11, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol FIS1

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