TSHR Antibody (TSHRA/1401) [Alexa Fluor® 405]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC, IHC-P, ICC/IF
Clone
TSHRA/1401
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 405

Order Details

TSHR Antibody (TSHRA/1401) [Alexa Fluor® 405] Summary

Immunogen
Recombinant human TSHR, A-Chain protein
Localization
Cytoplasmic
Marker
Thyroid Marker
Specificity
Thyroid-stimulating hormone (TSH, also known as thyrotropin) is a glycoprotein involved in the control of thyroid structure and metabolism, which stimulates the release of the thyroid hormones. TSH is regulated by thyroid hormone (T3) and various retinoid compounds. TSH binds to the thyroid-stimulating hormone receptor (TSHR), which is cleaved into two subunits, A and B, and plays a major role in regulating thyroid function. The third cytoplasmic loop of TSHR has been identified as critical for its role in regulating inositol phosphate and cAMP formation. In Graves disease, an autoimmune disorder, TSHR is activated by autoantibodies, which may be stimulated by the cleavage of the A and B subunits.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TSHR
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunofluorescence
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for TSHR Antibody (TSHRA/1401) [Alexa Fluor® 405]

  • CHNG1
  • LGR3
  • LGR3hTSHR-I
  • MGC75129
  • seven transmembrane helix receptor
  • thyroid stimulating hormone receptor
  • Thyroid-stimulating hormone receptor
  • thyrotropin receptor
  • thyrotropin receptor-I, hTSHR-I
  • TSH R
  • TSHR
  • TSH-R

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-49885AF350
Alexa Fluor 405 NBP2-49885AF405
Alexa Fluor 488 NBP2-49885AF488
Alexa Fluor 532 NBP2-49885AF532
Alexa Fluor 594 NBP2-49885AF594
Alexa Fluor 647 NBP2-49884AF647
Alexa Fluor 647 NBP2-49885AF647
Alexa Fluor 700 NBP2-49885AF700
Alexa Fluor 700 NBP2-49884AF700
Alexa Fluor 750 NBP2-49885AF750
Allophycocyanin NBP2-49885APC
Allophycocyanin NBP2-49884APC
Biotin NBP2-49884B
Biotin NBP2-49885B
DyLight 350 NBP2-49885UV
DyLight 405 NBP2-49885V
DyLight 488 NBP2-49885G
DyLight 550 NBP2-49885R
DyLight 594 NBP2-49885DL594
DyLight 650 NBP2-49885C
DyLight 680 NBP2-49885FR
DyLight 755 NBP2-49885IR
FITC NBP2-49885F
HRP NBP2-49885H
Janelia Fluor 549 NBP2-49885JF549
Janelia Fluor 646 NBP2-49885JF646
PE NBP2-49885PE
PerCP NBP2-49885PCP

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Contact Information

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Bioinformatics

Gene Symbol TSHR
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