TSH R Antibody (TSHRA/1401) [Allophycocyanin]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC-P
Clone
TSHRA/1401
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin

Order Details

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TSH R Antibody (TSHRA/1401) [Allophycocyanin] Summary

Immunogen
Recombinant human TSHR, A-Chain protein
Localization
Cytoplasmic
Marker
Thyroid Marker
Specificity
Thyroid-stimulating hormone (TSH, also known as thyrotropin) is a glycoprotein involved in the control of thyroid structure and metabolism, which stimulates the release of the thyroid hormones. TSH is regulated by thyroid hormone (T3) and various retinoid compounds. TSH binds to the thyroid-stimulating hormone receptor (TSHR), which is cleaved into two subunits, A and B, and plays a major role in regulating thyroid function. The third cytoplasmic loop of TSHR has been identified as critical for its role in regulating inositol phosphate and cAMP formation. In Graves disease, an autoimmune disorder, TSHR is activated by autoantibodies, which may be stimulated by the cleavage of the A and B subunits.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TSHR
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for TSH R Antibody (TSHRA/1401) [Allophycocyanin]

  • CHNG1
  • LGR3
  • LGR3hTSHR-I
  • MGC75129
  • seven transmembrane helix receptor
  • thyroid stimulating hormone receptor
  • Thyroid-stimulating hormone receptor
  • thyrotropin receptor
  • thyrotropin receptor-I, hTSHR-I
  • TSH R
  • TSHR
  • TSH-R

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Diseases for TSH R Antibody (NBP2-49884APC)

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Bioinformatics

Gene Symbol TSHR