TSH beta Antibody (11E4)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications S-ELISA
Clone
11E4
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

TSH beta Antibody (11E4) Summary

Immunogen
Full length native protein (purified) from human pituitary gland.
Specificity
This specifically recognizes the beta-subunit of human TSH.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TSHB
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Sandwich ELISA 1:100-1:2000
Application Notes
Recommended pairs (capture-detection): NB110-8274 - NB110-8275

Reactivity Notes

Cross-reacts with Human.Not yet tested in other species.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.4)
Preservative
0.09% Sodium Azide
Purity
Protein A purified

Notes

This antibody is now in-vitro produced. The amount of preservative has slightly decreased and all other specifications remain the same.

Alternate Names for TSH beta Antibody (11E4)

  • thyroid stimulating hormone, beta
  • thyroid-stimulating hormone subunit beta
  • thyrotropin beta chain
  • thyrotropin beta subunit
  • Thyrotropin beta
  • thyrotropin subunit beta
  • TSH beta
  • TSHB
  • TSH-B
  • TSH-BETA

Background

Thyroid-stimulating hormone (TSH), also known as thyrotropin, is secreted from cells in the anterior pituitary called thyrotrophs, finds its receptors on epithelial cells in the thyroid gland, and stimulates that gland to synthesize and release thyroid hormones. TSH is a glycoprotein hormone composed of two subunits which are non-covalently bound to one another. The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones, follicle-stimulating hormone and luteinizing hormone, and, in primates, in the placental hormone chorionic gonadotropin. Each of these hormones also has a unique beta subunit, which provides receptor specificity. In other words, TSH is composed of alpha subunit bound to the TSH beta subunit, and TSH associates only with its own receptor. Free alpha and beta subunits have essentially no biological activity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol TSHB
Entrez