Trypsin 3/PRSS3 Antibody (419910) [Alexa Fluor™ Plus 647]

• Clone: 419910
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor Plus 647

Trypsin 3/PRSS3 Antibody (419910) [Alexa Fluor™ Plus 647] Summary

• Specificity: Detects mouse Trypsin 3/PRSS3 in direct ELISAs and Western blots. In direct ELISAs and Western blots, weak cross-reactivity with recombinant human (rh) Trypsin 3 is observed and no cross-reactivity with rhTrypsin 1 or rhTrypsin 2 is observed.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Rat

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Trypsin 3/PRSS3 Antibody (419910) [Alexa Fluor™ Plus 647]

• Brain trypsinogen
• EC 3.4.21
• EC 3.4.21.4
• Mesotrypsin
• mesotrypsinogen
• MTG
• pancreatic trypsinogen III
• protease, serine, 3 (mesotrypsin)
• protease, serine, 3
• protease, serine, 4 (trypsin 4, brain)
• PRSS3
• PRSS4
• Serine protease 3
• Serine protease 4
• T9
• TRY3MTG
• TRY4mesotrypsin
• Trypsin 3
• Trypsin 4
• Trypsin III
• Trypsin IV
• trypsin-3
• Trypsinogen 15
• trypsinogen 4
• trypsinogen 5
• trypsinogen IV

Background

Trypsin 3, encoded by the PRSS3 gene and also known as mesotrypsin is a serine protease and is one of three pancreatic Trypsins. It constitutes less than 10% of the total Trypsin content in normal pancreatic juice. Trypsin 3 is activated by enterokinase cleavage of the 8 aa pro region and secreted into the duodenum lumen. Trypsin 3 is highly resistance to polypeptide Trypsin inhibitors, and may degrade them in foods to facilitate digestion. The 223 amino acid mature mouse Trypsin 3 shares 78% and 96% aa identity with human and rat Trypsin 3, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.