TRPC3 Antibody

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Product Details

Summary
Product Discontinued
View other related TRPC3 Primary Antibodies

Order Details


    • Catalog Number
      NB110-74982
    • Availability
      Product Discontinued

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TRPC3 Antibody Summary

Immunogen
A synthetic peptide as a part of human TRPC3 conjugated to immunogenic carrier protein was used as the immunogen.
Specificity
TRPC3.
Clonality
Polyclonal
Host
Sheep
Gene
TRPC3
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:300-1:4000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Positive Control
TRPC3 Lysate (NBL1-17331)

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Whole antisera
Preservative
No Preservative
Concentration
LYOPH
Purity
Unpurified
Reconstitution Instructions
Reconstitute with 0.1 ml sterilized water to desired concentration.

Alternate Names for TRPC3 Antibody

  • hTrp3
  • hTrp-3
  • short transient receptor potential channel 3
  • transient receptor potential cation channel, subfamily C, member 3
  • transient receptor potential channel 3
  • Transient receptor protein 3
  • TRP3
  • TRP-3
  • TrpC3

Background

FUNCTION: Thought to form a receptor-activated non-selective calcium permanent cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C, and by inositol-1,4,5-triphosphate receptors (ITPR) with bound IP3 (By similarity). May also be activated by internal calcium store depletion. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Probable). TISSUE SPECIFICITY: Abundantly expressed in brain. Concentrated in cerebellar Purkinje cells and sparsely localized in cerebellar granule lyer, pontine nuclei and thalamus. Lower levels detected in other tissues. SIMILARITY: Belongs to the transient receptor family, STrpC subfamily.; SIMILARITY: Contains 4 ANK repeats.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for TRPC3 Antibody (NB110-74982). (Showing 1 - 1 of 1 FAQ).

  1. I would like to test some of your TRPC3 antibodies in my model system (Xenopus), but they have not been proven to work in this species. Do you offer any guarantee, or beta testing program. We would be happy to send you any images we produce if the antibody works (WB, IHC, ICC). We know that TRPC1-5 are expressed in our system (Xenopus spinal cord).
    • We do offer a testing program, the Innovators Reward Program. Our Innovator’s Reward program is designed to support your innovative research with minimal financial risk to you. Should you decide to use one of our products in an application or species for which it has not been tested all you need to do is submit a full review of the antibody with an image to qualify.

Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Additional TRPC3 Products

Bioinformatics Tool for TRPC3 Antibody (NB110-74982)

Discover related pathways, diseases and genes to TRPC3 Antibody (NB110-74982). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for TRPC3 Antibody (NB110-74982)

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Pathways for TRPC3 Antibody (NB110-74982)

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PTMs for TRPC3 Antibody (NB110-74982)

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Blogs on TRPC3

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Contact Information

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Bioinformatics

Gene Symbol TRPC3
Entrez
Uniprot